Early Onset Fetal Growth Restriction: Does Path to Diagnosis Impact Outcomes and Pathology?

Archives of Obstetrics and Gynaecology
Brian BurnettJeff M Denney

Abstract

To evaluate demographics and outcomes of maternal-fetal pairs in early onset fetal growth restriction (FGR) requiring delivery prior to 34 weeks' gestation based on ultrasound indication leading to diagnosis. This is a descriptive study of maternal-fetal pairs with early FGR diagnosed prior to 30 weeks' gestation and delivering between 22w0d and 34w0d under the care of Wake Forest University Perinatology 01/2012-12/2016. Serial ultrasounds to assess fetal growth and umbilical artery flow Doppler velocimetry were evaluated. Pairs were dichotomized into those with maternal comorbidities leading to ultrasound diagnosis, and those with ultrasound indicated only by appreciation of uterine size less than dates on exam. Patient characteristics and outcomes were tracked. Univariate and multivariate analyses were performed as appropriate. 56 pregnancies were identified with FGR prior to 30 weeks and subsequent delivery prior to 34 weeks. Common comorbidities present in the group with maternal comorbidities included chronic hypertension (30.5%), hypertensive disorders of pregnancy (36.1%), preexisting diabetes (13.9%), gestational diabetes (5.6%). None of the women in the S<D group developed hypertensive disorders of pregnancy or GDM. Ot...Continue Reading

Methods Mentioned

BETA
cesarean section

Software Mentioned

REDCap ( Research Electronic Data Capture )
REDCap
OBGYN
STATA
AS

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