Early oral feeding after total laryngectomy: Outcome of 602 patients in one cancer center

Auris, Nasus, Larynx
Nilda Süslü, A Şefik Hoşal

Abstract

Pharyngocutaneous fistula (PCF) is the most frequent complication after total laryngectomy. However, delayed oral feeding and inserting a nasogastric tube has been considered as a safe practice among head and neck surgeons, and there is no general agreement on the initiation of the oral intake. The aim of the study is to determine the incidence of PCF after primary total laryngectomy in a large homogenous case series and to evaluate whether fistula and early oral feeding are related. Patients who underwent total laryngectomy/laryngopharyngectomy with primary closure of pharynx between 1990 and 2014 were reviewed. Patients who had a history of previous radiotherapy, chemotherapy or chemoradiotherapy, and patients who underwent more complex reconstruction techniques (e.g. pedicled or free flaps) for closure were excluded. In total, 602 patients underwent total laryngectomy (n=580) or total laryngectomy plus partial pharyngectomy (n=22). The overall PCF rate was 12%. In 582 of the 602 patients (99.8%), a nasogastric tube was not inserted. In 95.7% of the patients (576/602), oral feeding was started within 3 days of surgery. Among the patients who developed PCF (72/602), PCF rate was not significantly higher in early oral fed patie...Continue Reading

References

May 1, 1989·Head & Neck·S E Boyce, A D Meyers
Oct 1, 1994·The Annals of Otology, Rhinology, and Laryngology·G PapazoglouG Dokianakis
Feb 17, 1998·Head & Neck·L SoyluC Ozşahinoglu
Jun 1, 2000·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·J HerranzJ Gavilán
Nov 15, 2000·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·A L CavalotG Cortesina
Feb 24, 2001·Head & Neck·J A VirtaniemiV M Kosma
Feb 27, 2001·The Laryngoscope·J E Medina, A Khafif
Jun 5, 2003·The Laryngoscope·Huseyin SevenSuat Turgut
Jul 12, 2003·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Konstantinos D MarkouIoannis C Daniilidis
Jun 30, 2006·The Annals of Otology, Rhinology, and Laryngology·Kishore Chandra PrasadSatish Chandra
May 27, 2008·The Journal of Laryngology and Otology·J AswaniJ Fagan
Jun 19, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mitchell MachtayK Kian Ang
Nov 28, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Arlene A ForastiereJay S Cooper
Mar 13, 2015·Acta Oto-laryngologica·Nilda SüslüA Şefik Hoşal

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Citations

Jan 18, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Liset LansaatUNKNOWN Dutch Head and Neck Society
Feb 14, 2019·The Annals of Otology, Rhinology, and Laryngology·Omar H AhmedDavid Myssiorek
Jan 12, 2019·BMC Anesthesiology·Xiao-Dong ZhouQiang-Li Xie
Jul 16, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Juho NurkkalaJanne Liisanantti

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