Early Oral Feeding as Compared With Traditional Timing of Oral Feeding After Upper Gastrointestinal Surgery: A Systematic Review and Meta-analysis

Annals of Surgery
Kate F WillcuttsLaura D Byham-Gray

Abstract

To compare the effects of early oral feeding to traditional (or late) timing of oral feeding after upper gastrointestinal surgery on clinical outcomes. Early postoperative oral feeding is becoming more common, particularly as part of multimodal or fast-track protocols. However, concerns remain about the safety of early oral feeding after upper gastrointestinal surgery. Comprehensive literature searches were conducted across 5 databases from January 1980 until June 2015 without language restriction. Risk of bias of included studies was appraised and random-effects model meta-analyses were performed to synthesize outcomes of anastomotic leaks, pneumonia, nasogastric tube reinsertion, reoperation, readmissions, and mortality. Fifteen studies comprising 2112 adult patients met all the inclusion criteria. Mean hospital stay was significantly shorter in the early-fed group than in the late-fed group [weighted mean difference = -1.72 d, 95% confidence interval (CI) -1.25 to -2.20, P < 0.01). Postoperative length of stay was also significantly shorter (weighted mean difference = -1.44 d, 95% CI -0.68 to -2.20, P < 0.01). There was no significant difference in risk of anastomotic leak, pneumonia, nasogastric tube reinsertion, reoperatio...Continue Reading

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Citations

Jul 14, 2017·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Kevin M Elias
Jun 8, 2018·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Megan RattrayShelley Roberts
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May 11, 2018·Medical Oncology·Michał PędziwiatrAndrzej Budzyński
Mar 22, 2021·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Jakob BurcharthIsmail Gögenur
Mar 28, 2021·Journal of Cardiothoracic Surgery·Zhisheng JiangYi Shen
May 1, 2021·Journal of Clinical Medicine·Henry John Golder, Vassilios Papalois
Oct 30, 2016·Journal of Visceral Surgery·P Mariani, K Slim
Jul 10, 2021·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Arved WeimannPierre Singer
Jun 6, 2021·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·Lauren CarmichaelNicole Kiss
Oct 6, 2021·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Stephani JohnsonDavid A August

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