Early origins of cardiovascular disease in pediatric chronic kidney disease

Renal Failure
Hiren P Patel

Abstract

The importance of cardiovascular disease in adults with chronic kidney disease is now well recognized. For children who develop chronic kidney disease, cardiovascular disease is also a leading cause of eventual morbidity and mortality. Although the clinical manifestations of cardiovascular disease may not be apparent until later, early subclinical findings can be observed even during childhood. This review updates the reader on the epidemiology of cardiovascular disease in pediatric chronic kidney disease, discusses risk factors and potential mechanisms of accelerated cardiovascular disease, reviews evidence of early manifestations of cardiovascular disease in pediatric chronic kidney disease, and briefly discusses prevention and treatment strategies.

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Feb 14, 2021·The Canadian Journal of Cardiology·Bonita Falkner, Samuel Gidding
May 27, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Fatemeh Hamedi-KalajahiHossein Imani

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