Early Osteoarthritis After Untreated Anterior Meniscal Root Tears: An In Vivo Animal Study

Orthopaedic Journal of Sports Medicine
Brett D SteinemanTammy L Haut Donahue

Abstract

Meniscal root tears cause menisci and their insertions to inadequately distribute loads and potentially leave underlying articular cartilage unprotected. Untreated meniscal root tears are becoming increasingly recognized to induce joint degradation; however, little information is known about anterior meniscal root tears and how they affect joint tissue. To observe the early degenerative changes within the synovial fluid, menisci, tibial articular cartilage, and subchondral bone after arthroscopic creation of untreated anterior meniscal root tears. Controlled laboratory study. Anterolateral meniscal root tears were created in 1 knee joint of 5 adult Flemish Giant rabbits, and anteromedial meniscal root tears were created in 4 additional rabbits. The contralateral limbs were used as nonoperated controls. The animals were euthanized at 8 weeks postoperatively; synovial fluid was aspirated, and tissue samples of menisci and tibial articular cartilage were collected and processed for multiple analyses to detect signs of early degeneration. Significant changes were found within the synovial fluid, meniscal tissue, and tibial subchondral bone of the knees with anterior meniscal root tears when compared with controls. There were no sig...Continue Reading

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Citations

Apr 3, 2018·Journal of Experimental Orthopaedics·Johannes WeberJohannes Zellner
Sep 2, 2020·The American Journal of Sports Medicine·Scott C FaucettRobert F LaPrade

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