PMID: 16638355Apr 28, 2006Paper

Early outcome of orthotopic heart transplantation: a report of 21 cases

Zhonghua wai ke za zhi [Chinese journal of surgery]
Liang-wan ChenXiao-fu Dai

Abstract

To report the preliminary experience of 21 orthotopic heart transplantations without early death. Between April 2002 and June 2005, 21 patients underwent orthotopic heart transplantation. Recipients' pulmonary vascular resistance ranged from 3.0 to 5.9 wood units [mean (4.3 +/- 1.4) wood units]; Stanford myocardial protective solution or HTK solution was perfused for donor heart myocardial preservation, donor heart cold ischemic period ranged from 52 to 310 min [mean (81 +/- 23) min]; Three patients had previous cardiac operations under cardiopulmonary bypass, conventional Stanford orthotopic cardiac transplantation in 20 cases and total heart technique in 1 case; Recipients received simulect preoperatively and cyclosporine A, cellcept and prednisone postoperatively for prevention of acute allograft rejection; Patients received appropriate medical control of hypertension, hyperglycemia, hypercholesterolemia and uricacidemia. Acute right heart failure in 3 cases and pericardial effusion in 4 cases were observed at the early postoperative stage, but no any infection and acute rejection were found. All patients survived with good life quality. Heart transplantation may produce satisfying early results. Suitable selection of recipi...Continue Reading

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