Early oxygenation and ventilation measurements after pediatric cardiac arrest: lack of association with outcome

Critical Care Medicine
Kimberly Statler BennettPediatric Emergency Care Medicine Applied Research Network

Abstract

To explore oxygenation and ventilation status early after cardiac arrest in infants and children. We hypothesize that hyperoxia is common and associated with worse outcome after pediatric cardiac arrest. Retrospective cohort study. Fifteen hospitals within the Pediatric Emergency Care Applied Research Network. Children who suffered a cardiac arrest event and survived for at least 6 hours after return of circulation. None. Analysis of 195 events revealed that abnormalities in oxygenation and ventilation are common during the initial 6 hours after pediatric cardiac arrest. Hyperoxia was frequent, affecting 54% of patients. Normoxia was documented in 34% and hypoxia in 22% of patients. These percentages account for a 10% overlap of patients who had both hyperoxia and hypoxia. Ventilation status was more evenly distributed with hyperventilation observed in 38%, normoventilation in 29%, and hypoventilation in 46%, with a 13% overlap of patients who had both hyperventilation and hypoventilation. Derangements in both oxygenation and ventilation were common early after cardiac arrest such that both normoxia and normocarbia were documented in only 25 patients (13%). Neither oxygenation nor ventilation status was associated with outcome....Continue Reading

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