Early parenchymal contrast extravasation predicts subsequent hemorrhage progression, clinical deterioration, and need for surgery in patients with traumatic cerebral contusion

The Journal of Trauma
Abel Po-Hao HuangJui-Chang Tsai

Abstract

This study aimed to identify early radiologic signs that are predictive of hemorrhage progression and clinical deterioration in patients with traumatic cerebral contusion. We hypothesized that contrast extravasation (CE) and blood-brain barrier disruption might be associated with hemorrhage progression, brain edema, and clinical deterioration in these patients. Twenty-two patients with traumatic cerebral contusion (diagnosed on initial noncontrast head computed tomography [CT]) who initially did not require surgical intervention were enrolled in this study. Contrast-enhanced and perfusion CT scans were performed within 6 hours of injury, and follow-up noncontrast CT scans were performed at 24 hours and 72 hours. In each noncontrast CT scan, the volumes of the contusion hemorrhage and edema were calculated using computerized planimetric techniques. The initial Glasgow Coma Scale, hemorrhage progression, clinical deterioration, and the need for subsequent surgery were recorded. The early radiologic findings were compared with these parameters and functional outcome at 6 months to identify predictive radiologic signs. CE was present in 9 of 22 patients (41%) and was highly associated with hemorrhage progression (p < 0.05), clinica...Continue Reading

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Citations

Nov 26, 2013·Journal of Neurosurgery·Abel Po-Hao HuangMax Wintermark
Oct 20, 2012·AJNR. American Journal of Neuroradiology·L Letourneau-GuillonR I Aviv
Jul 15, 2016·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Hitoshi YamamuraYasumitsu Mizobata
Jan 29, 2020·AJR. American Journal of Roentgenology·Jai Jai Shiva ShankarRobert Vandorpe

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