Early patterning of the rat cerebral wall for regional organization of a neuronal population expressing latexin

Brain Research. Developmental Brain Research
Y Arimatsu, M Ishida

Abstract

The exact timing of regional patterning in the developing cerebral cortex and other telencephalic structures remains to be elucidated. In the present study, we addressed this issue by comparing the distribution and density of neuronal population expressing latexin in the adult rat telencephalon, with the regional pattern in the fetal cerebral wall as to the potential to generate latexin-expressing neurons. Immunohistochemical analyses on adult animals have shown that latexin-expressing neurons are restricted to a lateral cortical field, within which they are most abundant at the middle level, decreasing in number rostrally and caudally. Substantial numbers of latexin-immunopositive neurons were recorded in the claustrum and endopiriform nuclei, both of which are located from rostral to middle level in the lateral telencephalon. By examining the number and density of latexin-immunopositive neurons in organotypic slice cultures from various portions of the developing rat cerebral wall, it has been shown that the regional pattern within the early cerebral wall as to the potential to generate latexin-expressing neurons matches well the distribution and density of latexin-expressing neurons in the adult telencephalon. Thus, in cultu...Continue Reading

References

Oct 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·Y ArimatsuK Takiguchi-Hayashi
Oct 9, 1992·Science·N A O'RourkeS K McConnell
May 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·M F Barbe, P Levitt
Oct 1, 1989·Trends in Neurosciences·D D O'Leary
Jul 8, 1988·Science·P Rakic
Jun 1, 1994·The European Journal of Neuroscience·Y HatanakaY Arimatsu
Mar 31, 1994·Nature·M Cohen-TannoudjiM Wassef
Jan 1, 1994·Annual Review of Neuroscience·D D O'LearyR Tuttle
May 1, 1993·Cerebral Cortex·H Kennedy, C Dehay
Dec 5, 1995·Proceedings of the National Academy of Sciences of the United States of America·P Rakic
Dec 5, 1995·Proceedings of the National Academy of Sciences of the United States of America·E SorianoC Sotelo
Dec 19, 1995·Proceedings of the National Academy of Sciences of the United States of America·E NormantC Gros
Jan 1, 1997·Annual Review of Neuroscience·P LevittK L Eagleson

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Citations

Oct 2, 2002·Brain Research. Developmental Brain Research·Cécile Pinaudeau-NasarreMichel Roger
Aug 18, 2000·The European Journal of Neuroscience·C PinaudeauM Roger
Sep 4, 2015·The Journal of Physiological Sciences : JPS·Rena Orman
Apr 26, 2003·The European Journal of Neuroscience·Afsaneh GaillardMichel Roger
Oct 3, 2009·Annals of the New York Academy of Sciences·Gary Van Zant, Ying Liang
Oct 7, 2003·The Journal of Comparative Neurology·Yasuyoshi ArimatsuAkira Omori
Feb 13, 2001·Mechanisms of Development·S BulchandS Tole

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