PMID: 9426908Aug 1, 1997Paper

Early postburn fatty acid profile in burn patients

Burns : Journal of the International Society for Burn Injuries
O Cetinkale, Z Yazici

Abstract

To understand the alterations in lipid metabolism following burn injury, 29 patients with burns, 18 survivors for the first 15 days and 11 non-survivors until death, were studied for total fatty acid (FA) profiles. No specific dietary fat was given. The plasma total FA profile was determined by capillary gas chromatography. The main observations of this survey were that: arachidonic acid decreased by 55.7 per cent (P < 0.0002), and linoleic acid decreased by 31.6 per cent (P < 0.004), more immunosuppressive mediators were probably produced. The elevated levels of both palmitic (12.1 per cent increase, P < 0.02) and oleic acids (63.0 per cent increase, P < 0.0001) in the plasma of burned patients suggested increased lipolysis from depot triglycerides. Eicosatrienoic acid showed decreased levels (49.5 per cent decrease, P < 0.005) at 3-4 days. Docosahexaenoic acid reached its lowest level at postburn days 7-9 (32.1 per cent decrease, P < 0.04). The significant changes of FA profile in patients could be related to the increased activity of fat metabolism. The results of this study have revealed the basic FA changes and requirements. Overfeeding and unnecessary intake of the source of immunosuppressive mediators would be avoided.

References

Jan 1, 1992·World Journal of Surgery·E E Tredget, Y M Yu
Sep 1, 1991·Annals of Surgery·J T GrbicM L Rodrick
Jan 1, 1991·The Journal of Burn Care & Rehabilitation·M D PeckG F Babcock
Feb 1, 1990·Critical Care Medicine·J W Alexander, M M Gottschlich
Dec 1, 1990·The Journal of Trauma·J W Alexander
Jul 1, 1986·Annals of Surgery·J W AlexanderC K Ogle
Aug 1, 1987·Annals of Surgery·R R WolfeO B Holland
Aug 13, 1987·The New England Journal of Medicine·R R WolfeM Wolfe
Oct 1, 1974·Annals of Surgery·D W WilmoreB A Pruitt
Mar 1, 1984·The Journal of Trauma·J L Ninnemann, A E Stockland
Nov 1, 1984·The Journal of Trauma·A D GalsterW W Monafo
Nov 1, 1983·JPEN. Journal of Parenteral and Enteral Nutrition·R M AbelM L Grossman
Oct 1, 1983·Critical Care Medicine·J R HagemanC E Hunt
May 1, 1983·The Journal of Nutrition·M LocniskarP M Newberne
Mar 1, 1982·The Journal of Trauma·R L HarrisC R Baxter
Oct 1, 1993·The British Journal of Surgery·O CetinkaleA Pusane
Jun 1, 1996·Burns : Journal of the International Society for Burn Injuries·X S LiuA N Li

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Citations

Jun 7, 2008·Journal of Burn Care & Research : Official Publication of the American Burn Association·Bronwen Masters, Fiona Wood
Aug 18, 2009·Acta Paediatrica·M C MarínM J T de Alaniz
Jul 25, 2018·Stem Cells and Development·Brice MagneMarina Trouillas
Jul 20, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jureta W HortonDavid L Maass
Dec 17, 2016·Scientific Reports·Peter QiMarc G Jeschke
Jun 22, 2019·Oxidative Medicine and Cellular Longevity·Lingfei LiYuesheng Huang
Apr 26, 2021·Journal of Burn Care & Research : Official Publication of the American Burn Association·Matthew C MauckSamuel A McLean

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