PMID: 9527963Apr 7, 1998Paper

Early postoperative glucose control predicts nosocomial infection rate in diabetic patients

JPEN. Journal of Parenteral and Enteral Nutrition
J J PomposelliB R Bistrian

Abstract

To determined the relationship between perioperative glucose control and postoperative nosocomial infection rate is 100 consecutive diabetic patients undergoing elective surgery. One hundred initially uninfected diabetic patients undergoing elective surgery were prospectively monitored for perioperative glucose control and postoperative nosocomial infection rate. Glucose control was determined by the attending surgeon or diabetologist. A large tertiary care hospital that serves as the in-patient facility for a local diabetes center. All patients were screened for infection preoperatively. Only initially uninfected patients were enrolled, and all patients received perioperative antibiotic coverage. Perioperative glucose control and postoperative nosocomial infection rate were monitored prospectively. APACHE II scores were determined on all patients. Patients were stratified into two groups: those with relatively "good" perioperative glucose control (all values < or = 220 mg/dL) and those with "poor" control (at least one value > 220 mg/dL). Contingency tables were generated, comparing nosocomial infection rates vs perioperative glucose control. Correlation coefficients between APACHE II score and maximum and mean glucose values ...Continue Reading

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