Early Postoperative Oral Feeding After Total Gastrectomy in Gastric Carcinoma Patients: A Retrospective Before-After Study Using Propensity Score Matching

JPEN. Journal of Parenteral and Enteral Nutrition
Aelee Jang, Oh Jeong

Abstract

Despite its clinical benefits, early oral nutrition after total gastrectomy is not widely implemented because of concerns about tolerability and safety. We investigated the feasibility and safety of early oral nutrition after total gastrectomy in gastric carcinoma patients. This is a retrospective before-after study. From 2008-2016, 301 patients received conventional oral feeding (COF) before May 2012, and 454 patients, early oral feeding (EOF) after May 2012. The EOF group received oral diet on postoperative day 1, and the COF group was maintained nil-by-mouth until patients demonstrated gas passage. After balancing potential confounders using propensity score matching, 203 patients were selected in each group. Both matched groups demonstrated well-balanced baseline characteristics. The EOF group demonstrated significantly earlier first flatus time (2.9 vs 3.1 days, P = .013) and hospital discharge (8.9 vs 12.6 days, P < .001) than the COF group. No significant differences were observed for overall morbidity and mortality, but the EOF group demonstrated lower incidence of abdominal infection (3.0% vs 7.4%, P = .044) and anastomosis leakage (1.5% vs 4.9%, P = .048). Subgroup analyses by age, sex, operative approach, lymph node ...Continue Reading

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Citations

Jan 16, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·Ronald L Koretz
Jan 9, 2021·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Arved Weimann
Jul 10, 2021·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Arved WeimannPierre Singer

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