PMID: 10499690Sep 28, 1999Paper

Early predictors of myoglobinuria and acute renal failure following electrical injury

The Journal of Emergency Medicine
C L RosenR Sheridan

Abstract

Myoglobinuria-induced acute renal failure (ARF) is a potentially lethal consequence of electrical injury. We describe clinical variables that can predict the risk of myoglobinuria and ARF following electrical injury. This was a retrospective multivariate analysis of risk factors among electrically injured patients over a 26-year period. Urine myoglobin status was documented in 162 patients; 14% had myoglobinuria. No patient developed ARF. Multivariate modeling revealed that high-voltage exposure, prehospital cardiac arrest, full-thickness burns, and compartment syndrome were associated with myoglobinuria. Using a prediction rule defined as positive when a patient had > or = 2 risk factors yielded a sensitivity of 96% and negative predictive value of 99%. Electrical injury patients with myoglobinuria have little risk of developing ARF. A prediction rule can be used to screen out patients at low risk for myoglobinuria and identify high-risk patients who warrant early aggressive treatment and a more definitive myoglobin test.

References

Apr 1, 1977·American Journal of Surgery·J F BurkeR L Trelstad
Dec 1, 1978·American Journal of Surgery·C Wilkinson, M Wood
Jul 1, 1979·Archives of Internal Medicine·J F EneasM H Humphreys
Jul 1, 1977·American Journal of Surgery·E D Butler, T D Gant
Dec 1, 1991·Burns : Journal of the International Society for Burn Injuries·K M RamakrishnanT Mathivanen
Jan 1, 1991·Renal Failure·K L GuptaK S Chugh
Jul 1, 1990·Plastic and Reconstructive Surgery·D L BhattR C Lee
Mar 22, 1990·The New England Journal of Medicine·O S Better, J H Stein
Jan 1, 1989·Intensive Care Medicine·G R NimmoA D Cumming
Jun 8, 1985·British Medical Journal·S Devereux, S M Knowles
May 27, 1974·JAMA : the Journal of the American Medical Association·J W Yost, F F Holmes
Oct 17, 1974·The New England Journal of Medicine·R A GrossmanM Goldberg
Nov 1, 1974·American Journal of Surgery·C P Artz
Jan 1, 1969·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·G von Bahr
Apr 1, 1984·Annals of Plastic Surgery·E A Luce, S E Gottlieb
Jan 1, 1984·Scandinavian Journal of Plastic and Reconstructive Surgery·G Arturson, A Hedlund
Jan 1, 1993·Nephron·G H MalikM Altaf
Apr 1, 1954·British Journal of Plastic Surgery·R H DALE
Jul 1, 1962·The Journal of Trauma·P H TAYLORE H VOGEL
Jan 1, 1965·Archives of Environmental Health·M M FISHER, H E TEBROCK

❮ Previous
Next ❯

Citations

Apr 12, 2001·The Journal of Emergency Medicine·M Sungur, M Güven
Jun 26, 2007·Critical Care : the Official Journal of the Critical Care Forum·Sean M BagshawUNKNOWN ANZICS Database Management Committee
Aug 3, 2014·The Surgical Clinics of North America·Shawn P FaganJeremy Goverman
Mar 19, 2005·Critical Care : the Official Journal of the Critical Care Forum·Ana L Huerta-AlardínPaul E Marik
Oct 23, 2010·Burns : Journal of the International Society for Burn Injuries·Peter L StollwerckFrank Siemers
Jan 5, 2002·The Surgical Clinics of North America·M OrlinskyM D Kerstein
Jun 24, 2004·Best Practice & Research. Clinical Anaesthesiology·Edward R Sherwood, Tracy Toliver-Kinsky
Apr 27, 2017·European Heart Journal·Victor WaldmannEloi Marijon
May 3, 2019·The Journal of Trauma and Acute Care Surgery·Christopher J Andrews, Dorin Panescu
Feb 21, 2018·Annals of Plastic Surgery·Derek M CulnanWilliam C Lineaweaver

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved