Early presentation of type 2 diabetes in Mexican-American youth

Diabetes Care
N D NeufeldC M Vadheim

Abstract

To describe features of pediatric-onset type 2 diabetes in the Hispanic population. The medical records of 55 Hispanic subjects with diabetes who were treated from 1990 to 1994 in a pediatric clinic serving lower income Mexican-Americans were reviewed to assess the frequency and clinical features of type 2 diabetes. Additionally, nondiabetic siblings of several patients underwent oral glucose tolerance testing, and a survey of six high schools in the same county was performed. Seventeen of 55 (31%) of the diabetic children and adolescents had type 2 diabetes. An additional 4 Hispanic children with type 2 diabetes treated in other clinics were also identified, yielding a total of 21 subjects who were used to describe the characteristics of childhood type 2 diabetes. At presentation, all were obese (mean BMI 32.9 +/- 6.2 kg/m2), 62% had no ketonuria, and fasting C-peptide levels were elevated (4.28 +/- 3.43 ng/ml). Diabetes was easily controlled with diet, sulfonylureas, or low-dose insulin. No autoantibodies were present in those tested, and family histories were positive for type 2 diabetes. Compliance was poor, and 3 subjects developed diabetic complications. Of the tested siblings, 2 of 8 had impaired glucose tolerance and 5 ...Continue Reading

Citations

May 8, 2002·Diabetes/metabolism Research and Reviews·Rebecca LiptonSally Freels
May 8, 2002·Diabetes/metabolism Research and Reviews·Anne Peters Harmel
Jul 4, 2006·Maternal and Child Health Journal·Michelle D OwensFarah M Chowdhury
Dec 30, 2006·Reviews in Endocrine & Metabolic Disorders·Daniel E Hale, Guadalupe Rupert
May 24, 2003·Current Diabetes Reports·J H Silverstein, A L Rosenbloom
Dec 3, 2002·The American Journal of Medicine·Carlos A Aguilar-SalinasJuan A Rull
Oct 8, 1999·Clinica Chimica Acta; International Journal of Clinical Chemistry·A Fagot-CampagnaD F Williamson
Nov 5, 1999·Obstetrics and Gynecology·E C KiefferA Ventura
Feb 19, 2003·Diabetes Research and Clinical Practice·Jung-Nan WeiFung-Chang Sung
Jun 16, 1999·Diabetes Research and Clinical Practice·N M McGrathP Dawson
Apr 15, 2008·Trends in Endocrinology and Metabolism : TEM·S Arslanian, K Danadian
Jul 19, 2006·Journal of Health Communication·Kathleen J KellyGabriel R Gonzalez
Mar 5, 2003·Diabetes Technology & Therapeutics·William E WinterDesmond Schatz
Aug 16, 2000·Current Opinion in Pediatrics·S T Callahan, M J Mansfield
Oct 22, 2010·The Journal of Clinical Endocrinology and Metabolism·Kenneth C CopelandUNKNOWN TODAY Study Group
Apr 19, 2005·Treatments in Endocrinology·Neslihan Gungor, Silva Arslanian
Oct 17, 2012·The Angle Orthodontist·J von BremenS Ruf
Jun 13, 2014·Current Diabetes Reports·Elizabeth R Pulgaron, Alan M Delamater
Nov 2, 2006·American Journal of Public Health·Edith C KiefferWilliam H Herman
Sep 4, 2007·Acta Diabetologica·Shuichi OtabeKentaro Yamada
Dec 29, 2004·Postgraduate Medicine·Manuel Idrogo, Roger Mazze
Sep 25, 1999·Pediatric Annals·I Libman, S A Arslanian
Oct 25, 2008·Molecular and Cellular Endocrinology·Sharell M Bindom, Eric Lazartigues
Nov 27, 2007·Journal of Pediatric Nursing·Nancy M SweeneyTige Leivas
Jan 20, 2007·Journal of Pediatric Nursing·Ruth C McGillis BindlerRobert Short
Jan 17, 2007·Metabolism: Clinical and Experimental·Ebenezer NyenweChukwuma Ogugua
Nov 23, 2005·Pediatric Clinics of North America·Neslihan GungorSilva Arslanian
Aug 12, 2004·Pharmacotherapy·Allyson S Gaylor, Michelle E Condren
Sep 24, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·V ZdravkovicJ Hamilton
Jul 14, 2004·Progress in Cardiovascular Nursing·Laurie Quinn
Sep 24, 2005·The Journal of School Health·Howard Taras, William Potts-Datema
Dec 25, 2004·Journal of the American Academy of Nurse Practitioners·M Anette HagartyJacquelyn M Clement
Sep 29, 2004·Pediatric Diabetes·R SinghP Zimmet
Mar 31, 2004·Journal of Clinical Pharmacology·Nathaniel Winer, James R Sowers
Mar 11, 2004·Journal of Paediatrics and Child Health·S HotuT Cundy
Dec 6, 2003·Pediatric Diabetes·Ingrid M Libman, Dorothy J Becker
Sep 17, 2009·Pediatric Diabetes·Joseph WolfsdorfRagnar Hanas
Jan 9, 2004·Pediatric Diabetes·Lorrene D RitchieSharon E Fleming
Mar 8, 2007·Pediatric Diabetes·Joseph WolfsdorfUNKNOWN International Society for Pediatric and Adolescent Diabetes
Jan 3, 2008·Pediatric Diabetes·Orit Pinhas-Hamiel, Phil Zeitler
Jan 5, 2005·Clinical Cornerstone·Daniel E Hale
Jan 10, 2006·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Diane BerryMargaret Grey

❮ Previous
Next ❯

Related Concepts

Related Feeds

American Diabetes Association Journals

Discover the latest diabetes research published by the journals from the American Diabetes Association.

Biomarkers for Type 2 Diabetes

Biomarkers can help understand chronic diseases and assist in risk prediction for prevention and early detection of diseases. Here is the latest research on biomarkers in type 2 diabetes, a disease in which the body is unable to produce or properly use insulin.