PMID: 11322375Apr 27, 2001Paper

Early prognostic factors of infants with chronic renal failure caused by renal dysplasia

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
K IsmailiF Janssen

Abstract

Renal dysplasia (RD) is a common cause of chronic renal failure (CRF) in children. The evolution towards end-stage renal failure is unpredictable due to the paucity of early prognostic factors. In order to identify early prognostic clinical criteria, we have retrospectively analyzed renal function and growth in 11 infants with RD and CRF from birth up to 4 years of age. Children with obstructive RD were not included. Glomerular filtration rate (GFR) was estimated from Schwartz formula. In infants with a GFR below 15 ml/min per 1.73 m2 at 6 months of age (group A, n=5), kidney function did not further improve; 4 reached end-stage renal failure between 8 months and 6 years of age. In contrast, infants with a GFR above 15 ml/min per 1.73 m2 at 6 months of age (group B, n=6) experienced a significant improvement in renal function during follow-up, and none required renal replacement therapy. During the first 3 months of life all infants with RD and CRF developed severe growth retardation. Between 6 months and 4 years of age, children from group B grew significantly better than those from group A. In conclusion, our experience suggests that GFR, estimated from Schwartz formula at 6 months of age, is a useful prognostic factor in inf...Continue Reading

Citations

Dec 18, 2001·Prenatal Diagnosis·P Winyard, L Chitty
Nov 30, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Miroslav ZivicnjakUwe Querfeld
Apr 16, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Doris FrankeJochen H H Ehrich
Mar 8, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Rosemary ThomasAli G Gharavi
Oct 12, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Aleksandra M ZurowskaUNKNOWN European Paediatric Dialysis Working Group
Mar 29, 2002·Kidney International·Douglas G MatsellAlice F Tarantal
Feb 12, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Tran Thi Mong HiepAnnie Robert
Dec 5, 2009·Clinical and Experimental Nephrology·UNKNOWN Japanese Society of Nephrology
Dec 11, 2007·Seminars in Fetal & Neonatal Medicine·Paul Winyard, Lyn S Chitty
Aug 3, 2011·Journal of Neurosciences in Rural Practice·Rudrajit PaulAmit Kumar Banerjee
Dec 6, 2001·Current Opinion in Urology·M J Kemper, D E Müller-Wiefel
Apr 16, 2020·Journal of Developmental Origins of Health and Disease·Sonja BrennanYogavijayan Kandasamy
May 17, 2003·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ifeoma Anochie, Felicia Eke
Sep 11, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Claudio La ScolaGiovanni Montini
Jun 26, 2017·Journal of Nephrology·Giovanni MontiniUNKNOWN European Society for Paediatric Nephrology Working Group on Congenital Anomalies of the Kidney and Urinary Tract
Jun 19, 2021·Seminars in Nephrology·Eduardo A OliveiraRobert H Mak

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