Early recognition of neuroleptic malignant syndrome during traumatic brain injury rehabilitation

Brain Injury : [BI]
Vivek KadyanW Jerry Mysiw

Abstract

Neuroleptic malignant syndrome is a rare disorder that manifests with hyperthermia, muscle rigidity and autonomic instability. Presented is a case series of individuals with traumatic brain injury and agitation who, when treated with neuroleptics, developed neuroleptic malignant syndrome. Although the incidence of this syndrome is rare, it is associated with significant morbidity and mortality. The onset of symptoms inconsistent with the patient's current level of recovery should alert the clinician to consider other possible diagnosis and failure to distinguish the features of neuroleptic malignant syndrome from post-traumatic agitation will delay appropriate intervention for this potentially life-threatening disorder.

References

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Citations

Apr 28, 2005·International Journal of Nursing Practice·Sarah MottMarita Kenrick
Dec 15, 2010·PM & R : the Journal of Injury, Function, and Rehabilitation·Percival H PangilinanJoseph Edward Hornyak
Sep 24, 2004·American Journal of Physical Medicine & Rehabilitation·Vivek KadyanDaniel M Clinchot
Oct 6, 2005·American Journal of Physical Medicine & Rehabilitation·Lisa A Lombard, Ross D Zafonte
Jul 31, 2013·Neurocritical Care·Axel Petzold, Armand Girbes
Mar 12, 2009·The Journal of Trauma·Cassandra J BellamyAmy L Seybert

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