Early referral recommendations for ankylosing spondylitis (including pre-radiographic and radiographic forms) in primary care

Annals of the Rheumatic Diseases
J Sieper, M Rudwaleit


An earlier diagnosis of ankylosing spondylitis (AS) is required because there is still a 5-7 year delay between first symptoms and diagnosis, and new effective treatments are available for active disease. Primary care physicians need easy to apply parameters to help them identify patients with suspected AS for onward referral. The best measures found were inflammatory back pain and HLA-B27 positivity.

Associated Clinical Trials


Aug 1, 1979·Acta Orthopaedica Scandinavica·I Jajić
Jun 13, 1977·JAMA : the Journal of the American Medical Association·A CalinD J Schurman
Sep 1, 1987·Clinical Rheumatology·W MauH Deicher
Jan 1, 1982·Annals of Internal Medicine·M A Khan, M K Khan
Nov 1, 1995·British Journal of Rheumatology·M R Underwood, P Dawes
Jan 20, 1998·Arthritis and Rheumatism·J BraunJ Sieper
Jan 19, 1999·Rheumatic Diseases Clinics of North America·S van der Linden, D van der Heijde
Feb 15, 2001·The New England Journal of Medicine·R A Deyo, J N Weinstein
May 22, 2003·Annals of the Rheumatic Diseases·A van TubergenSj van der Linden
Nov 13, 2003·Arthritis and Rheumatism·John C DavisUNKNOWN Enbrel Ankylosing Spondylitis Study Group
Dec 16, 2003·Annals of the Rheumatic Diseases·C G MullighanP G Bardy
Apr 15, 2004·Annals of the Rheumatic Diseases·M RudwaleitJ Sieper
Dec 21, 2004·Annals of the Rheumatic Diseases·H HaibelJ Sieper

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