PMID: 7547015Sep 1, 1995Paper

Early remodelling of coronary stenoses after thrombolytic treatment in patients with acute myocardial infarction

British Heart Journal
D TousoulisG J Davies

Abstract

To assess the frequency of early remodelling of coronary stenosis morphology after thrombolytic treatment in patients with acute myocardial infarction. Coronary angiograms were analysed by a computerised edge detection analysis system. Coronary stenosis severity was measured and morphology classified as smooth or complex. Coronary arteriograms were obtained approximately 90 min and 24 h after thrombolytic treatment from 40 patients with acute myocardial infarction. Stenosis morphology was complex in 22 patients (65%) and smooth in 11 (32%) 90 min after thrombolysis. The morphology of 11 (50%) complex coronary stenoses and three (27%) smooth stenoses had changed at 24 h (P < 0.05). The transition from complex to smooth was associated with a reduction in stenosis severity from 65 (4)% to 51 (5)% (P < 0.05). The stenosis severity was 63 (4)% and 60 (5)% in those with persistently complex morphology, and 56 (7)% and 50 (5)% in those with persistently smooth morphology at 90 min and 24 h respectively (NS). Transition of morphology from complex to smooth within 24 h is common. This transition is associated with a reduction in stenosis severity of a degree greater than that found in persistently smooth stenoses over the same interval....Continue Reading

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Citations

Jan 18, 2006·Zeitschrift für Kardiologie·S Silber, B M Richartz
Jun 20, 2008·AJR. American Journal of Roentgenology·Jason L KellySharmila C Lingam
Feb 22, 2005·Atherosclerosis·Claudia MonacoJohn F Martin
Nov 6, 2007·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Ian GrahamUNKNOWN European Atherosclerosis Society (EAS)
Mar 6, 2010·Atherosclerosis·Yuri Sheikine, Kamran Akram

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