Early results from a randomized clinical trial of colon J pouch versus transverse coloplasty pouch after low anterior resection for rectal cancer

The British Journal of Surgery
A B UlrichM W Büchler

Abstract

Patients with primary rectal cancer undergoing low anterior resection are often reconstructed using a pouch procedure. The aim of this trial was to compare colon J pouch (CJP) with transverse coloplasty pouch (TCP) reconstruction with regard to functional results, perioperative mortality and morbidity. As there is considerable uncertainty over the true anastomotic leak rate in patients with a TCP, the study analysed short-term outcome data. Elective patients suitable for either procedure after sphincter-saving low anterior resection were eligible. Randomization took place during surgery. The primary endpoint was the rate of late evacuation problems after 2 years; secondary endpoints were anastomotic leak rate, perioperative morbidity and mortality. Between 21 October 2002 and 5 December 2005, 149 patients were randomized. All 76 patients randomized to TCP had the procedure compared with 68 of the 73 patients (93 percent) randomized to CJP. Both groups were comparable with regard to demographic and clinical characteristics. Surgical complications (CJP: 19 percent; TCP: 18 percent) and the overall anastomotic leak rate (8 percent) were equally distributed in both groups. This trial demonstrated a comparable early outcome for TCP ...Continue Reading

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Citations

Mar 27, 2010·Surgery Today·Jin-ichi Hida, Kiyotaka Okuno
Jun 27, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C LiaoD Wu
Apr 10, 2009·The British Journal of Surgery·M BlockT Oresland
Jul 8, 2016·Acta chirurgica Belgica·Audrius DulskasNarimantas E Samalavicius
Aug 27, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·L Di CristofaroM Scarpa
Apr 11, 2012·CA: a Cancer Journal for Clinicians·Lauren KosinskiRodrigo Perez
Apr 3, 2015·The British Journal of Surgery·F J HüttnerA Ulrich
Jul 28, 2020·Langenbeck's Archives of Surgery·Fabio NoceraDaniel C Steinemann
Nov 17, 2009·Surgical Oncology Clinics of North America·Jason ParkW Douglas Wong

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