Early Social Cognitive Ability in Preschoolers with Prader-Willi Syndrome and Autism Spectrum Disorder

Journal of Autism and Developmental Disorders
Anastasia DimitropoulosSandra W Russ

Abstract

Children with Prader-Willi syndrome (PWS) and autism spectrum disorder (ASD) present with challenges in social cognitive ability, Research comparing PWS to ASD is important given the implication of 15q11-q13 region in the biology of autism. However, recent findings question the accuracy of relying solely on parent report in behavioral characterization. Thus, this study examined social cognition in an observable pretend play task and by parent report in 50 preschool children (ages 3-5) with PWS, by subtype, compared to ASD. Behaviorally, the paternal deletion subtype expressed overall higher functioning, whereas the maternal uniparental disomy subtype performed more similarly to the ASD group. Results are the first to show deficits in social cognitive ability early in development. The severity and differences in deficits between PWS subtypes are important in informing early intervention efforts.

References

Mar 1, 1990·Journal of Autism and Developmental Disorders·P MundyC Kasari
Jun 3, 1999·Journal of Clinical Child Psychology·A L Seja, S W Russ
May 24, 2000·Cognition·H Tager-Flusberg, K Sullivan
Jun 24, 2003·Journal of the American Academy of Child and Adolescent Psychiatry·Erika L NurmiJames S Sutcliffe
Aug 20, 2003·Biostatistics·Carolyn M Rutter, Diana L Miglioretti
Dec 18, 2003·Autism : the International Journal of Research and Practice·Christopher Jarrold
Apr 29, 2005·Autism : the International Journal of Research and Practice·Daryl J HigginsJulian C Pearce
Nov 15, 2006·Journal of Intellectual Disability Research : JIDR·D E Gray
Dec 30, 2006·Journal of Autism and Developmental Disorders·Susan Williams WhiteLawrence Scahill
Feb 6, 2007·Current Opinion in Neurobiology·Daniel H Geschwind, Pat Levitt
Mar 29, 2007·Current Psychiatry Reports·Anastasia Dimitropoulos, Robert T Schultz
Oct 9, 2008·Neurobiology of Disease·Amber HogartN Carolyn Schanen
Nov 6, 2008·Social Cognitive and Affective Neuroscience·Suparna ChoudhuryTony Charman
Jan 28, 2010·International Journal of Language & Communication Disorders·Kristelle HudryUNKNOWN PACT Consortium
Sep 13, 2011·American Journal on Intellectual and Developmental Disabilities·Somer L BishopCatherine Lord
May 12, 2012·Journal of Autism and Developmental Disorders·Anastasia DimitropoulosBenjamin Feldman
Jan 9, 2013·Journal of Communication Disorders·Anastasia DimitropoulosMaria Lemler
Sep 23, 2014·Journal of Autism and Developmental Disorders·Olena ZygaAnastasia Dimitropoulos
May 1, 2008·Perspectives on Psychological Science : a Journal of the Association for Psychological Science·Kristina R Olson, Carol S Dweck
Mar 8, 2017·International Journal of Molecular Sciences·Jeffrey A BennettLonnie Zwaigenbaum
Jun 9, 2017·Journal of Neurodevelopmental Disorders·Elisabeth M DykensSoo-Jeong Kim

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Citations

May 26, 2021·Brain Connectivity·Kenichi YamadaMasaki Watanabe
Jun 22, 2021·Journal of Neurodevelopmental Disorders·Lauren SchwartzKate Woodcock
Nov 16, 2021·Frontiers in Molecular Neuroscience·A Kaitlyn VictorLawrence T Reiter

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