Early symptoms of systemic lupus erythematosus (SLE) recalled by 339 SLE patients

Lupus
N Leuchten; on behalf of the SLE Classification Criteria Steering Committee

Abstract

Objective The European League Against Rheumatism and the American College of Rheumatology jointly embarked on a new classification criteria for systemic lupus erythematosus (SLE) project. Its first phase involved generation of a broad set of items potentially useful for classification of SLE. This study was undertaken to add the patient perspective to an expert Delphi approach and an early patient cohort study. Methods A national cross-sectional study was conducted. A self-report questionnaire was published in the "Schmetterling" (Butterfly), the quarterly journal of the German SLE patient association. Individuals with SLE were asked to anonymously complete the questionnaire, which asked for demographic details, organ manifestations, autoantibodies and symptoms. Results A total of 339 completed questionnaires out of 2498 were returned, a response rate of 13.6%; 83.2% reported they were ANA positive and 81.7% reported joint, 66.1% skin and 33.0% renal involvement. For the time before and in the first year after their SLE diagnosis, the majority reported fatigue (89.4%), joint pain (86.7%), photosensitivity (79.4%) and myalgia (76.1%). Of interest, more than half of the patients reported fever as an early symptom (53.7%). Conclus...Continue Reading

References

Nov 1, 1982·Arthritis and Rheumatism·E M TanR J Winchester
Jan 1, 1993·Nihon rinsho. Japanese journal of clinical medicine·K NagaokaS Ozaki

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Citations

Jan 30, 2019·Annals of the Rheumatic Diseases·Sara K TedeschiKaren H Costenbader
Aug 11, 2019·Lupus·M Y Choi, M J Fritzler
Nov 30, 2018·Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry·Abdel Masieh MetrySuad Hannawi
Feb 26, 2020·Lupus Science & Medicine·Nancy J Olsen, David R Karp
May 14, 2019·Lupus Science & Medicine·Michael D LockshinMary K Crow
Sep 15, 2020·Current Opinion in Rheumatology·Martin Aringer, Michelle Petri
May 15, 2020·Current Rheumatology Reports·Martin AringerSindhu R Johnson
Sep 29, 2019·Arthritis Care & Research·Zahi ToumaUNKNOWN ACR/EULAR group, New SLE classification criteria for clinical research are being developed, sponsored by EULAR, ACR
Dec 7, 2020·Rheumatology·Martin Aringer, Sindhu R Johnson
Dec 8, 2019·Best Practice & Research. Clinical Rheumatology·Mariele GattoAndrea Doria
Jan 30, 2021·Der Internist·Martin Aringer, Matthias Schneider
Jan 25, 2021·The Journal of Allergy and Clinical Immunology·Matthew T PatrickLam C Tsoi
Mar 20, 2021·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Martin Aringer, Matthias Schneider

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