Early T1 Myocardial MRI Mapping: Value in Detecting Myocardial Hyperemia in Acute Myocarditis

Radiology
Anna PalmisanoAntonio Esposito

Abstract

Background Hyperemia is a key component of acute myocarditis (AM). Early gadolinium uptake because of myocardial hyperemia may be quantified by using T1 mapping. Purpose To evaluate the value of early enhanced T1 shortening for the diagnosis of acute myocarditis. Materials and Methods Study participants suspected of having AM and healthy control (HC) participants were prospectively enrolled from September 2016 to May 2019. Participants underwent 1.5-T cardiac MRI including Lake Louise criteria, T2 mapping, native T1, and extracellular volume, with the addition of early enhanced T1 mapping (2 minutes after intravenous administration of 0.15 mmol/kg gadobutrol). Color-coded maps of the percentage of T1 shortening from precontrast to early postcontrast were generated. Optimal early T1 shortening cut-off value and its diagnostic performance in the identification of acute myocarditis were calculated. Results Forty-five study participants with AM (median age, 40 years; interquartile range [IQR], 20-46 years; 22 women) diagnosed according to multidisciplinary clinical evaluation, electrocardiography, laboratory test, echocardiography, cardiac MRI, and coronary CT and/or invasive angiography. Findings were confirmed by endomyocardial b...Continue Reading

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Citations

Jul 23, 2020·Journal of Computer Assisted Tomography·Francesco SecchiFrancesco Sardanelli
Aug 9, 2020·JACC. Cardiovascular Imaging·Eustachio AgricolaFrancesco De Cobelli
Nov 16, 2020·The International Journal of Cardiovascular Imaging·Giulia CundariMarco Francone
Mar 12, 2020·Radiology·Carlo N De Cecco, Caterina B Monti
Aug 29, 2021·Trends in Cardiovascular Medicine·Sanaz AsadianMohammad Mehdi Hemmati Komasi

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