Early treatment of a quetiapine and sertraline overdose with Intralipid

Anaesthesia
S D H FinnN Sable

Abstract

We describe the initial management and subsequent recovery of a 61 year-old male patient following attempted suicide by oral ingestion of a potentially fatal overdose of quetiapine and sertraline. Intravenous Intralipid was given soon after initiation of basic resuscitation. There was a rapid improvement in the patient's level of consciousness. No other clinical signs of drug toxicity were observed. Intralipid may have reversed the deep coma associated with ingestion and prevented other manifestations of drug toxicity occurring, thus expediting this patient's recovery.

Associated Clinical Trials

References

Nov 27, 2002·The American Journal of Psychiatry·Praveen P Fernandes, William A Marcil
Mar 31, 2005·Emergency Medicine Australasia : EMA·Grant CaveCraig D Castle
Jan 27, 2006·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Simon TebbuttGrant Cave
Nov 14, 2006·Annals of Emergency Medicine·Martyn Harvey, Grant Cave
Dec 29, 2006·Toxicological Reviews·Guy Weinberg
Feb 3, 2007·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Theodore C BaniaIn-Hei Hahn
Feb 28, 2007·Anesthesiology·Rudolph H de Jong
Jan 24, 2008·Anaesthesia·S Mathieu, J Cranshaw
Feb 27, 2008·Regional Anesthesia and Pain Medicine·Thomas McCutchen, J C Gerancher
Mar 25, 2008·Annals of Emergency Medicine·Grant Cave, Martyn Harvey
Apr 25, 2008·Annals of Emergency Medicine·Adeline NgoKent R Olson
Jun 24, 2008·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Martyn G Harvey, Grant R Cave
Jun 28, 2008·Anaesthesia·J A W Wildsmith

❮ Previous
Next ❯

Citations

Oct 7, 2010·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Leelach RothschildGuy Weinberg
Jul 23, 2013·Anesthesia and Analgesia·Katherine A PooleMichael Aziz
Dec 18, 2013·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Michael LevineAnthony F Pizon
Dec 18, 2013·Annals of Emergency Medicine·Stephanie CarreiroJason B Hack
Jun 4, 2014·Pediatric Emergency Care·Mark A Kostic, Marc Gorelick
Jan 15, 2014·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Grant CaveGuy Weinberg
Jul 8, 2009·Current Opinion in Anaesthesiology·Ulana Leskiw, Guy L Weinberg
Nov 3, 2011·Journal of the American Veterinary Medical Association·Dana L ClarkeErica L Reineke
Feb 16, 2013·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Stephanie CarreiroJason B Hack
May 11, 2013·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Michael R ChristianMark B Mycyk
Jun 19, 2009·Critical Care Medicine·Grant Cave, Martyn Harvey
Jul 19, 2013·Critical Care Medicine·Jingyuan LiMansoureh Eghbali
Mar 23, 2010·Regional Anesthesia and Pain Medicine·David B HillerGuy L Weinberg
Feb 3, 2012·International Journal of Emergency Medicine·Martyn Harvey, Grant Cave
Sep 5, 2012·Expert Review of Clinical Pharmacology·W Stephen Waring
Jan 9, 2014·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·M HarveyB Ong
Feb 9, 2016·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Michael LevineUNKNOWN Lipid Emulsion Workgroup
Jan 26, 2010·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Chloé JamatyJean-Marc Chauny
Mar 3, 2012·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Lukas Lannemyr, Kai Knudsen
Oct 11, 2011·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Deborah FrenchAlan H B Wu
May 14, 2011·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Deborah FrenchAlan H B Wu
Jun 1, 2014·Critical Care Nursing Clinics of North America·Dinesh YogaratnamMichael DiNapoli
Mar 14, 2013·Journal of Emergency Nursing : JEN : Official Publication of the Emergency Department Nurses Association·Michael N PerzaJamie M Rosini
Mar 3, 2012·The Veterinary Clinics of North America. Small Animal Practice·Sharon Gwaltney-Brant, Irina Meadows
Nov 30, 2010·International Journal of Obstetric Anesthesia·P Toledo
Dec 1, 2009·Emergency Medicine Clinics of North America·Craig G Smollin
Oct 7, 2009·Resuscitation·J McKevith, A Banks
Jun 8, 2015·Journal of Anesthesia·Sam H MullerAlan David Kaye
Mar 15, 2016·The Journal of Emergency Medicine·Samuel H F LamGary M Vilke
Oct 23, 2009·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Grant Cave, Martyn Harvey
Jul 25, 2009·Anaesthesia·G Weinberg
Aug 19, 2009·Anaesthesia·J Picard, W Harrop-Griffiths
Aug 19, 2009·Anaesthesia·P WattL Dyson
Jan 16, 2009·Anaesthesia·J Picard, W Harrop-Griffiths
Dec 12, 2012·Anaesthesia·G T C Wong, M G Irwin
Aug 11, 2011·Journal of Veterinary Emergency and Critical Care·Alberto L FernandezKristin Engebretsen
Nov 15, 2011·Anaesthesia·R Jakkala-SaibabaG L Morton
Apr 15, 2011·Emergency Medicine Australasia : EMA·Grant CaveAndis Graudins
Jan 16, 2013·Journal of Veterinary Emergency and Critical Care·Steven E Epstein, Steven R Hollingsworth
Dec 17, 2009·Emergency Medicine Australasia : EMA·Martyn Harvey, Grant Cave
Apr 21, 2010·Anaesthesia·N A Smith

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.