Early Use of Anti-influenza Medications in Hospitalized Children With Tracheostomy

Pediatrics
Ryo MiyakawaChristopher J Russell

Abstract

Early administration of anti-influenza medications is recommended for all children hospitalized with influenza. We investigated whether early use of anti-influenza medications is associated with improved outcomes in children with tracheostomy hospitalized with influenza. We performed a multicenter retrospective cohort study through the Pediatric Health Information System database for patients aged 30 days to 19 years who were discharged between October 1, 2007, and September 30, 2015 with diagnostic codes for both influenza and tracheostomy. Our primary predictor was receipt of anti-influenza medications on hospital day 0 or 1. We used propensity score matching to adjust for confounding by indication. Primary outcomes were length of stay (LOS) and 30-day all-cause revisit rate (emergency department visit or hospital admission). Of 1436 discharges screened, 899 met inclusion criteria. The median admission age was 5 years (interquartile range: 2-10). The majority had multiple complex chronic conditions (median 3; interquartile range: 3-4) and technology dependence, such as gastrostomy tube (73.6%). After matching 772 unique admissions by propensity score, LOS was shorter for the cohort receiving early anti-influenza medications (...Continue Reading

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Citations

Jul 4, 2021·The Journal of Pediatrics·James W AntoonDerek J Williams
Sep 9, 2021·Pediatrics·UNKNOWN COMMITTEE ON INFECTIOUS DISEASES
Sep 9, 2021·Pediatrics·UNKNOWN COMMITTEE ON INFECTIOUS DISEASES
Sep 4, 2019·Pediatrics·UNKNOWN COMMITTEE ON INFECTIOUS DISEASES
Sep 23, 2021·Pediatrics·Kayur MehtaUNKNOWN Canadian Immunization Monitoring Program Active (IMPACT) Investigators

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