Early variation of quick sequential organ failure assessment score to predict in-hospital mortality in emergency department patients with suspected infection

European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine
Najla LemachattiFrench Society of Emergency Medicine Collaborators Group and the INFURGSEMES Group

Abstract

The quick sequential organ failure assessment (qSOFA) score showed good prognostic performance in patients with suspicion of infection in the emergency department (ED). However, previous studies only assessed the performance of individual values of qSOFA during the ED stay. As this score may vary over short timeframes, the optimal time of measurement, and the prognostic value of its variation are unclear. The objective of the present study was to prospectively assess the prognostic value of the change in qSOFA over the first 3 h (ΔqSOFA = qSOFA at 3 h-qSOFA at inclusion). This is an international prospective cohort study conducted in 17 EDs in France, Belgium, and Spain. From November 2016 to March 2017, patients with a suspected infection and a qSOFA score of 2 or higher were included and followed up until death or hospital discharge. qSOFA was measured at inclusion, 1 h and 3 h. Primary end point was in-hospital mortality, truncated at 28 days. Of 534 recruited patients, 512 were included in the analysis. The qSOFA was improved at 3 h (ΔqSOFA < 0) in 287 (55%) patients. Overall in-hospital mortality was 27%: 44% when ΔqSOFA greater than 0, 36% when ΔqSOFA = 0, and 18% when ΔqSOFA less than 0. A positive ΔqSOFA was independent...Continue Reading

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Citations

Dec 19, 2019·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Yonathan Freund
Aug 30, 2019·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Duncan Sebastian HargreavesLuke Eliot Hodgson
Feb 26, 2020·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Céline Occelli, Julie Contenti
Jun 27, 2019·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Juan González-Del CastilloFrancisco J Martín-Sánchez
Aug 28, 2020·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Céline Occelli, Julie Contenti
Oct 24, 2020·International Journal of Clinical Practice·Raúl López-IzquierdoCarlos Del Pozo Vegas
May 23, 2019·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Yonathan FreundLuis Garcia-Castrillo

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