Early Versus Delayed Feeding in Patients With Acute Pancreatitis: A Systematic Review

Annals of Internal Medicine
Valerie M VaughnVineet Chopra

Abstract

Acute pancreatitis is among the most common and costly reasons for hospitalization in the United States. Bowel rest, pain control, and intravenous fluids are the cornerstones of treatment, but early feeding might also be beneficial. To compare length of hospital stay, mortality, and readmission in adults hospitalized with pancreatitis who received early versus delayed feeding. MEDLINE via Ovid, EMBASE, the Cochrane Library, CINAHL, and Web of Science through January 2017. Two authors independently reviewed and selected studies if they were randomized clinical trials, included adults hospitalized with acute pancreatitis, and compared early versus delayed feeding (≤48 vs. >48 hours after hospitalization). Two investigators independently extracted study data and rated risk of bias using the Cochrane Collaboration tool. Eleven randomized trials (8 peer-reviewed publications, 3 abstract-only presentations) that included 948 patients were eligible. Seven trials (3 with low risk of bias) enrolled patients with mild to moderate pancreatitis. Four trials (1 with low risk of bias) included patients with predicted severe pancreatitis. Routes used for early feeding included oral (4 studies), nasogastric (2 studies), nasojejunal (4 studies)...Continue Reading

Citations

Jun 8, 2018·Current Opinion in Critical Care·Yaseen M Arabi, Hasan M Al-Dorzi
Aug 17, 2018·Pancreas·Mary BarbaraLaura Rosenkranz
Jan 11, 2019·Pancreas·Elizabeth DongBechien U Wu
Sep 20, 2019·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Meera Ramanathan, Abdul Aziz Aadam
Aug 15, 2018·Journal of Clinical Gastroenterology·Zhouxiang JinJisheng Wang
Mar 19, 2020·JPEN. Journal of Parenteral and Enteral Nutrition·Xinrong ChenKa Li
Jun 9, 2020·Addiction·Paul S Haber, Nicholas C Kortt
Jan 30, 2018·JPEN. Journal of Parenteral and Enteral Nutrition·Desheng QiMilin Peng
Jul 28, 2019·Journal of Clinical Medicine·Lena J StorckPeter E Ballmer
Nov 23, 2017·JPEN. Journal of Parenteral and Enteral Nutrition·Ronald L Koretz
May 30, 2019·Nature Reviews. Gastroenterology & Hepatology·Peter J Lee, Georgios I Papachristou
Feb 1, 2019·Current Treatment Options in Gastroenterology·Mahya FaghihVikesh K Singh
Jan 21, 2021·AJR. American Journal of Roentgenology·Amir Ata Rahnemai-AzarSidhartha Tavri
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Mar 7, 2021·Journal of Clinical Medicine·Allison L Yang
Feb 27, 2021·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Jorge D MachicadoDhiraj Yadav
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May 1, 2021·Nutrients·Beata Jabłońska, Sławomir Mrowiec
Sep 21, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Pedram ParagomiGeorgios I Papachristou

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