PMID: 1099184Oct 1, 1975Paper

Early versus late introduction of continuous negative pressure in the management of the idiopathic respiratory distress syndrome

The Journal of Pediatrics
P GerardP H Beaudry


To evaluate the effectiveness of the early application of continuous negative pressure about the thorax, 23 infants with the idiopathic respiratory distress syndrome who had adequate alveolar ventilation were assigned to early or late application of CNP. There were 11 infants in the early CNP and 12 in the late CNP group. There were no differences between the two groups with respect to birth weight, gestational age, age at admission to the study, initial FIO2 requirements, or initial PaO2, PaCo2, and AaPO2. None of the ENCP patients required mechanical ventilation, whereas four of the LCNP group did so. The FIO2 requirements were significantly less for the ECNP infants when compared to the LCNP ones. The mean duration of FIO2 requirements greater than 0.6 was 28.3 hours for those receiving ECNP and 60.7 hours for those in LCNP (P LESS THAN 0.05). This study suggests that the course of RDS may be modified by the early application of CNP.


Aug 1, 1972·The Journal of Pediatrics·E W OuterbridgeL Stern
Jun 17, 1971·The New England Journal of Medicine·G A GregoryW K Hamilton
Nov 1, 1970·Acta paediatrica Scandinavica·J Senterre, P Karlberg
Jan 1, 1960·Scandinavian Journal of Clinical and Laboratory Investigation·O S ANDERSENP ASTRUP

❮ Previous
Next ❯


Jul 8, 1998·Pediatric Clinics of North America·M C McGettiganJ P Goldsmith
Jan 1, 1978·Acta Anaesthesiologica Scandinavica·J Kamper, A Brendstrup
May 1, 1977·Archives of Disease in Childhood·L P AllenP D Wimberley
Jul 1, 1977·Archives of Disease in Childhood·A K TanswellB T Smith
Nov 1, 1979·Archives of Disease in Childhood·N R Roberton
Dec 5, 2002·Seminars in Neonatology : SN·Richard A Polin, Rakesh Sahni
Jan 1, 1991·International Journal of Technology Assessment in Health Care·A Jonzon
Jan 1, 1997·Journal of Perinatal Medicine·F C Battaglia, A M Marconi
Oct 16, 2020·The Cochrane Database of Systematic Reviews·Jacqueline J HoPeter G Davis

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.