Early vs late tracheostomy in critically ill patients: a systematic review and meta-analysis

The Clinical Respiratory Journal
Liang MengJian Zhang

Abstract

This study aims to compare the outcomes of early tracheostomy (ET) (≤10 days after translaryngeal intubation) with late tracheostomy (LT) (>10 days after translaryngeal intubation) in critically ill patients with prolonged mechanical ventilation (MV). We searched PubMed, EMBASE and the Cochrane Library from inception to April 2014. We included all randomized controlled trials (RCTs), which compared ET with LT in critically ill patients. There was no language restriction. Two authors extracted data and conducted a quality assessment. Meta-analyses using the fixed-effects or random-effects model were conducted for mortality, incidence of ventilator-associated pneumonia (VAP), duration of MV and sedation, length of intensive care unit (ICU) stay. We enrolled 9 studies, in which a total of 2040 patients were randomized to either ET group (N = 1018) or LT group (N = 1022). ET might reduce the duration of sedation [weighted mean difference (WMD) = -5.99 days; 95% confidence intervals (CI) = -11.41 to -0.57 days; P = 0.03]. ET did not significantly alter the mortality [relative risk (RR) = 0.88; 95% CI = 0.76-1.00; P = 0.06], incidence of VAP (RR = 0.84; 95% CI = 0.66-1.08; P = 0.17), duration of MV (WMD = -4.46 days; 95% CI = -12.61 ...Continue Reading

References

Feb 1, 1984·The Journal of Trauma·C M Dunham, C LaMonica
Feb 1, 1996·Controlled Clinical Trials·A R JadadH J McQuay
Dec 9, 1997·The Journal of Trauma·H J SugermanS Schaffer
May 12, 2000·American Journal of Respiratory and Critical Care Medicine·A EstebanM J Tobin
Nov 15, 2002·The Journal of Burn Care & Rehabilitation·Jeffrey R SaffleLinda Edelman
Oct 11, 2003·Clinics in Chest Medicine·John E Heffner
Sep 4, 2004·The Journal of Trauma·Moulay Ahmed BouderkaAbdeslam Harti
Jul 2, 2008·Intensive Care Medicine·François BlotAgnès Laplanche
Oct 22, 2008·Anesthesia and Analgesia·Stefan KlugeGeorg Kreymann
Apr 22, 2010·JAMA : the Journal of the American Medical Association·Pier Paolo TerragniV Marco Ranieri
Mar 16, 2012·The Cochrane Database of Systematic Reviews·Brenda Nazaré Gomes SilvaOrsine Valente
Jan 26, 2013·Medicina intensiva·J M AñónUNKNOWN Grupo de Trabajo de Insuficiencia Respiratoria Aguda de la SEMICYUC
May 23, 2013·JAMA : the Journal of the American Medical Association·Duncan YoungUNKNOWN TracMan Collaborators
Oct 1, 2013·Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih·Liang ShanLian-di Li
Mar 29, 2014·PloS One·Huibin HuangJiandong Lin

❮ Previous
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Citations

Dec 5, 2015·Critical Care : the Official Journal of the Critical Care Forum·Koji HosokawaJean-Louis Vincent
Dec 12, 2017·F1000Research·Jean-Francois TimsitBruno Mourvllier
Nov 8, 2017·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Radovan UvizlPetr Jakubec
Jan 9, 2018·Journal of Intensive Care·Michael P CatalinoJ Dedrick Jordan
Nov 27, 2019·Critical Care Medicine·Ahmed Abdelaal Ahmed Mahmoud M AlkhatipDina Zakaria
Apr 22, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Arunjit TakharPavol Surda
Jun 27, 2019·Laryngoscope Investigative Otolaryngology·Hirotomo DochiYasushi Furuta
Jan 16, 2020·Critical Care Medicine·Ahmed Abdelaal Ahmed Mahmoud M AlkhatipDina Zakaria
Jan 1, 2017·Current Trauma Reports·Morgan Schellenberg, Kenji Inaba
Jul 29, 2020·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Suma RadhakrishnanMohammed Shareef Ponneth
Sep 29, 2020·Frontiers in Neurology·Alessandro PincherleKarin Diserens
Mar 30, 2017·Case Reports in Critical Care·Pragya PunjChristopher R Newey
Apr 24, 2018·Journal of Intensive Care Medicine·Shawn P E NishiGulshan Sharma
May 5, 2017·Intensive Care Medicine·Demosthenes MakrisSaad Nseir
Jun 12, 2020·American Journal of Speech-language Pathology·Charissa J ZagaMichael J Brenner
Aug 18, 2018·Critical Care : the Official Journal of the Critical Care Forum·Toshikazu AbeUNKNOWN LUNG-SAFE Investigators and the ESICM Trials Group
Nov 7, 2018·Medizinische Klinik, Intensivmedizin und Notfallmedizin·J GrensemannS Kluge
Jul 28, 2020·Clinical and Experimental Otorhinolaryngology·UNKNOWN Korean Bronchoesophagological Society Guideline Task ForceDong Il Sun
Nov 12, 2020·Ear, Nose, & Throat Journal·Massimo Mesolella
Dec 11, 2020·Khirurgiia·Yu G StarkovA A Zvereva
Jul 30, 2020·American Journal of Infection Control·Taikan NanaoToshio Ogawa
Feb 20, 2021·Clinical Neurology and Neurosurgery·Sabrina Araujo de FrancaManoel J Teixeira
Sep 24, 2020·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Sachin GuptaKanchi Vv Gupta
Mar 25, 2020·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Sachin GuptaSushma Gurav
Jul 3, 2021·Journal of Clinical Medicine·Denise BattagliniPaolo Pelosi
Jul 9, 2021·Critical Care : the Official Journal of the Critical Care Forum·Matthieu SchmidtUNKNOWN International ECMO Network (ECMONet)
Jul 21, 2021·BMJ Surgery, Interventions, & Health Technologies·UNKNOWN COVIDTrach collaborative
Oct 13, 2021·Journal of Intensive Care Medicine·Christopher M KappChristoph T Hutchinson
Dec 11, 2020·Respiration; International Review of Thoracic Diseases·Bernd SchönhoferWolfram Windisch

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