East-west differences and migration in Finland: Association with cardiometabolic risk markers and IMT. The Cardiovascular Risk in Young Finns Study

Scandinavian Journal of Public Health
Lauri VähämurtoOlli T Raitakari

Abstract

Coronary heart disease mortality has been internationally high in eastern Finland. The excessive mortality risk in Eastern compared with western Finns is explained by differences in cardiometabolic risk profile. Current risk profile differences and association with migration have not been reported. We examined the association of place of residence (east-west) and specifically migration with cardiometabolic risk markers and carotid intima-media thickness (IMT). The study population included 2204 participants with data available from childhood/youth in 1980 and follow-up examination in 2007. Participants residing in eastern Finland in adulthood had 0.022±0.004mm higher IMT than Western participants. Those who migrated east-to-west had lower IMT than those staying in the east (0.027±0.006mm, p<0.0001) while no difference to those continuously living in the west was found. Those who moved east-to-west had a lower body mass index (25.3±4.3 kg/m(2) vs. 26.2±4.5kg/m(2), p=0.01), waist circumference (85.7±12.8cm vs. 88.6±12.8cm, p=0.001), prevalence of metabolic syndrome (13% vs. 21%, p=0.01), and higher socioeconomic status (16.6±3.3 vs. 15.0±3.3 school years, p<0.0001) than those who stayed in the east. CONCLUSIONS HIGHER IMT WAS FOU...Continue Reading

References

Mar 1, 1984·Preventive Medicine·A KeysN Kimura
Feb 1, 1994·Hypertension·N J Birkett
Oct 16, 1999·Arteriosclerosis, Thrombosis, and Vascular Biology·K S WooD S Celermajer
Nov 19, 2002·International Journal of Epidemiology·S Goya WannametheeMary Walker
Apr 14, 2006·Journal of Hypertension·Mika J KastarinenErkki A Vartiainen
Feb 12, 2008·International Journal of Epidemiology·Olli T RaitakariJorma S A Viikari
Dec 5, 2009·International Journal of Epidemiology·Erkki VartiainenPekka Puska
Jan 10, 2012·Arteriosclerosis, Thrombosis, and Vascular Biology·Paula KestiläOlli T Raitakari
Jan 4, 2013·Diabetes Care·UNKNOWN American Diabetes Association
Oct 15, 2013·Medicine and Science in Sports and Exercise·Risto TelamaOlli T Raitakari

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Citations

Aug 30, 2019·Scandinavian Journal of Public Health·Joel NuotioMarkus Juonala

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