Easy retrieval of single amino-acid polymorphisms and phenotype information using SwissVar.

Bioinformatics
Anaïs MottazYum L Yip

Abstract

The SwissVar portal provides access to a comprehensive collection of single amino acid polymorphisms and diseases in the UniProtKB/Swiss-Prot database via a unique search engine. In particular, it gives direct access to the newly improved Swiss-Prot variant pages. The key strength of this portal is that it provides a possibility to query for similar diseases, as well as the underlying protein products and the molecular details of each variant. In the context of the recently proposed molecular view on diseases, the SwissVar portal should be in a unique position to provide valuable information for researchers and to advance research in this area. The SwissVar portal is available at www.expasy.org/swissvar anais.mottaz@isb-sib.ch; lina.yip@isb-sib.ch Supplementary data are available at Bioinformatics online.

References

Mar 9, 2007·Nature Biotechnology·Kasper LageSøren Brunak
Jan 4, 2008·Journal of Bioinformatics and Computational Biology·Yum Lina YipAnne-Lise Veuthey
Feb 5, 2008·Trends in Genetics : TIG·Martin OtiHan G Brunner
May 9, 2008·BMC Bioinformatics·Antonio JimenoDietrich Rebholz-Schuhmann
May 9, 2008·BMC Bioinformatics·Anaïs MottazAnne-Lise Veuthey
Sep 20, 2008·BMC Bioinformatics·Vinayak KulkarniHarold R Garner
Oct 7, 2008·Nucleic Acids Research·UNKNOWN UniProt Consortium
Oct 28, 2008·American Journal of Human Genetics·Peter N RobinsonStefan Mundlos

❮ Previous
Next ❯

Citations

Feb 26, 2011·Journal of Cardiovascular Translational Research·Sungsam GongTom L Blundell
Jan 17, 2012·Briefings in Bioinformatics·Emidio CapriottiYana Bromberg
Oct 14, 2010·Bioinformatics·Loredana Le PeraAnna Tramontano
Apr 12, 2012·Database : the Journal of Biological Databases and Curation·Tien-Dao LuuHoan Nguyen
Nov 8, 2012·Genome Biology and Evolution·Onuralp Soylemez, Fyodor A Kondrashov
May 30, 2012·Nucleic Acids Research·Tien-Dao LuuHoan Nguyen
May 4, 2012·Journal of the Royal Society, Interface·Jennifer L LahtiRuss B Altman
Jul 13, 2012·BMC Genomics·Christian SchaeferBurkhard Rost
Jul 17, 2013·BMC Genomics·Emidio CapriottiYana Bromberg
Jul 25, 2014·PloS One·Petros KountourisMarina Kleanthous
Mar 22, 2014·Journal of Proteome Research·Surendra DasariAhmet Dogan
Sep 19, 2014·Nucleic Acids Research·Yang PanRaja Mazumder
Nov 29, 2015·Nucleic Acids Research·Holger DinkelToby J Gibson
Feb 24, 2016·Drug Metabolism and Personalized Therapy·Grace Shema NzabonimpaUNKNOWN INDICES Consortium
Dec 4, 2013·Nucleic Acids Research·Sungsam GongStuart A Cook
Jul 29, 2016·Molecular Genetics & Genomic Medicine·Eva KönigFrancisco S Domingues
Nov 8, 2014·Briefings in Bioinformatics·Jiajia ChenBairong Shen
May 3, 2016·Cell Systems·Ju Hun YeonJörg Gsponer
Jun 11, 2016·Protein Engineering, Design & Selection : PEDS·Antonia StankRebecca C Wade
Jan 20, 2017·Human Mutation·Emidio CapriottiRita Casadio
Dec 13, 2017·Journal of Molecular Recognition : JMR·A KulandaisamyM Michael Gromiha
Aug 5, 2017·Metabolic Brain Disease·Neerja GuptaMadhulika Kabra
Feb 6, 2018·Bioinformatics·A KulandaisamyM Michael Gromiha
May 11, 2019·PLoS Computational Biology·Jung Eun ShimInsuk Lee
May 16, 2020·PLoS Computational Biology·Jimin PeiNick V Grishin
Apr 12, 2019·Briefings in Bioinformatics·Saman ZeeshanZeeshan Ahmed
May 6, 2020·Human Mutation·Jorge E KolomenskiLiliana Dain
May 3, 2012·Clinical Pharmacology and Therapeutics·P Cordero, E A Ashley

❮ Previous
Next ❯

Software Mentioned

SwissVar
Perl
PostgreSQL
SSMAP
CGI

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.