Eating disorders and biochemical composition of saliva: a retrospective matched case-control study

European Journal of Oral Sciences
Ann-Katrin JohanssonAnders Johansson

Abstract

This study aimed to compare the biochemical composition of saliva from patients with eating disorders (EDs) with saliva from control subjects with no ED. All patients who initiated outpatient treatment in an ED clinic during a 12-month period were invited to participate. Of the 65 patients who started treatment during the period, 54 (50 female patients/four male patients; mean age: 21.5 yr) agreed to participate. The controls were 54 sex- and age-matched patients from a dental health clinic. All participants completed a questionnaire and underwent dental clinical examinations, including laboratory analyses of saliva. The proportion of subjects with unstimulated salivary hyposalivation was lower in the ED group and not correlated with intake of xerogenic drugs. Significant differences in the biochemical composition of saliva were found almost exclusively in the unstimulated state, with albumin, inorganic phosphate, aspartate aminotransferase (ASAT), chloride, magnesium, and total protein all being significantly higher in the ED group. Conditional logistic regression showed that higher ASAT and total protein concentrations were relatively good predictors of ED, with sensitivity and specificity of 65% and 67%, respectively. In con...Continue Reading

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Feb 1, 2012·European Journal of Oral Sciences·Ann-Katrin JohanssonAnders Johansson
Apr 30, 2013·The International Journal of Eating Disorders·Ana Paula HermontSheyla Márcia Auad

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Citations

Feb 16, 2016·The International Journal of Eating Disorders·K Jean ForneyGuido K W Frank
Mar 5, 2020·Journal of Eating Disorders·Ann-Katrin JohanssonAnders Johansson
Jun 7, 2019·Eating and Weight Disorders : EWD·Ricardo N M J PáscoaPedro S Gomes
Sep 1, 2021·Periodontology 2000·Hélène RangéPhilippe Bouchard

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Software Mentioned

SPSS
Statistical Package for the Social Sciences SPSS

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