EBV-positive, HHV8-negative large B-cell lymphoma with an unusual germinotropic growth pattern in an immunocompetent patient

Clinical Case Reports
Saja K AsakrahChristine R Bryke

Abstract

Clinicopathologic and cytogenetic findings of an unusual EBV+ve, HHV8-ve germinotropic lymphoma, with a nongerminal center immunophenotype occurring in an immunocompetent individual, are presented. A comprehensive literature search revealed a single report of three similar cases. These may represent a unique subset of EBV-positive large B-cell lymphomas in immunocompetent individuals.

References

Oct 18, 2002·Blood·Ming-Qing DuPeter G Isaacson
Sep 6, 2011·Clinical Lymphoma, Myeloma & Leukemia·Brady E BeltranJorge J Castillo
Mar 4, 2014·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Chi Young OkKen H Young
Jan 15, 2016·Virchows Archiv : an International Journal of Pathology·Luisa LorenziFabio Facchetti
Dec 17, 2016·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Nicholas MackridesJennifer Chapman
Mar 2, 2017·The American Journal of Surgical Pathology·Tapan BhavsarElaine S Jaffe

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Methods Mentioned

BETA
biopsy
flow cytometry

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