Eccrine porocarcinoma of the head: an important differential diagnosis in the elderly patient

Dermatology : International Journal for Clinical and Investigative Dermatology
Peter Arne GerberDaniela Bruch-Gerharz

Abstract

Eccrine porocarcinoma is a rare malignant tumor of the sweat gland, characterized by a broad spectrum of clinicopathologic presentations. Surprisingly, unlike its benign counterpart eccrine poroma, eccrine porocarcinoma is seldom found in areas with a high density of eccrine sweat glands, like the palms or soles. Instead, eccrine porocarcinoma frequently occurs on the lower extremities, trunk and abdomen, but also on the head, resembling various other skin tumors, as illustrated in the patients described herein. We report 5 cases of eccrine porocarcinoma of the head. All patients were initially diagnosed as having epidermal or melanocytic skin tumors. Only after histopathologic examination were they classified as eccrine porocarcinoma, showing features of epithelial tumors with abortive ductal differentiation. Characteristic clinical, histopathologic and immunohistochemical findings of eccrine porocarcinomas are illustrated. Eccrine porocarcinomas are potentially fatal adnexal malignancies, in which extensive metastatic dissemination may occur. Porocarcinomas are commonly overlooked, or misinterpreted as squamous or basal cell carcinomas as well as other common malignant and even benign skin tumors. Knowledge of the clinical pa...Continue Reading

References

Apr 1, 1992·The American Journal of Dermatopathology·O TellecheaA P Baptista
Jan 1, 1991·Dermatologica·E AkiyoshiA Hidano
Apr 1, 1988·Annals of Plastic Surgery·H S MatloubH Y Choi
Jul 1, 1986·The British Journal of Dermatology·L PuttickJ S Comaish
Dec 1, 1982·The British Journal of Dermatology·M ShawM M Black
Feb 1, 1993·Journal of Cutaneous Pathology·J P ReisA P Baptista
Jan 1, 1997·European Radiology·R SigalD Vanel
Jul 7, 1999·Dermatology : International Journal for Clinical and Investigative Dermatology·H GrimmeW Vanscheidt
Dec 14, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·G P WittenbergC V Washington
May 3, 2001·Annals of Oncology : Official Journal of the European Society for Medical Oncology·T A PlunkettR D Rubens
Jun 8, 2001·The American Journal of Surgical Pathology·A RobsonE Calonje
Sep 25, 2001·Medical and Pediatric Oncology·K ValverdeH S Chan
Jan 29, 2002·The American Journal of Surgical Pathology·Cristian PernaFélix Contreras
May 22, 2002·Lancet·Bettina HelmkeBernd Rüdiger Balda
Oct 25, 2003·Journal of the American Academy of Dermatology·Rajat GoelMichael L Wallace
Jun 16, 2004·Journal of the European Academy of Dermatology and Venereology : JEADV·J GutermuthN Haas
Jun 25, 2004·The British Journal of Dermatology·I NemotoH Shimizu
Feb 25, 2005·The British Journal of Dermatology·S B ChoK Y Chung
Apr 7, 2007·The American Journal of Dermatopathology·Omer GünhanUğur Berberoğlu

❮ Previous
Next ❯

Citations

Mar 7, 2014·Archives of Dermatological Research·Jinane El KhouryOssama Abbas
Mar 18, 2011·World Journal of Surgical Oncology·Ugo MaroneNicola Mozzillo
May 1, 2009·Diagnostic Cytopathology·Limin YuXin Jing
Jun 13, 2018·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Azadeh NazemiAshley Wysong
Jul 17, 2009·The Kaohsiung Journal of Medical Sciences·Ning-Chia Chang, Kun-Bow Tsai
Apr 22, 2020·Head & Neck·Nguyen-Son LeBoban M Erovic

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Carcinoma, Basal Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

B-Cell Leukemia (Keystone)

B-cell leukemia includes various types of lymphoid leukemia that affect B cells. Here is the latest research on B-cell leukemia.

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Related Papers

Ophthalmic Plastic and Reconstructive Surgery
Rajeev JainDinesh Selva
Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
A J McMichael, J Gay
Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Thomas KlenznerCarsten Christof Boedeker
© 2021 Meta ULC. All rights reserved