PMID: 6167137Jan 1, 1981Paper

Eccrine sweat glands are not innervated in hereditary sensory neuropathy type IV. An electron-microscopic study

Acta Neuropathologica
J LangerS Veit

Abstract

The ultrastructural study of a skin biopsy in a patient afflicted with hereditary sensory neuropathy type IV (congenital insensitivity to pain with anhidrosis) did not reveal any unmyelinated axons or axonal terminals around eccrine sweat glands but only processes, partially covered by a basement membrane and therefore resembling Schwann cell processes. The absence of such unmyelinated axons in close proximity to eccrine sweat glands where they normally occur appears to be the morphological equivalent to the anhidrosis and also corresponds to the deficiency of unmyelinated axons in the sural nerve of the same patient, as previously reported.

References

May 1, 1980·Muscle & Nerve·E RafelJ Lazo
Nov 1, 1980·Journal of Neuropathology and Experimental Neurology·H H GoebelP J Dyck

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Citations

Apr 1, 1995·Pediatric Neurology·N TachiK Minagawa
Aug 3, 2001·Pediatric Neurology·L SztrihaI Masouyé
Nov 7, 1998·Pediatric Neurology·M BerkovitchE Lahat
Aug 30, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M NolanoG Caruso
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Jan 1, 1992·The Australasian Journal of Dermatology·J HatzisJ Stratigos
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Oct 5, 2007·Orphanet Journal of Rare Diseases·Felicia B Axelrod, Gabrielle Gold-von Simson
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Mar 19, 2013·Pediatric Neurology·Zamir ShorerJacov Levy
Mar 27, 2007·The British Journal of Dermatology·M OgataY Narisawa
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Sep 18, 2016·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Babar KayaniDeborah M Eastwood
Jan 25, 2012·Nature Reviews. Neurology·Annelies RotthierKatrien Janssens
Mar 17, 2012·Journal of Pediatric Orthopedics. Part B·Ilias KosmidisKonstantinos Filiopoulos
May 20, 2015·Journal of Pediatric Gastroenterology and Nutrition·Qingli WangXianwei Zhang
Mar 7, 2020·Hand : Official Journal of the American Association for Hand Surgery·Michelle SpiteriHenk Giele
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Feb 11, 1998·Brain Pathology·C Ceuterick-de Groote, J J Martin
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Nov 17, 2017·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Aykut UrfaliogluAyşe Balaban

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