Echo-based Single Point Imaging (ESPI): a novel pulsed EPR imaging modality for high spatial resolution and quantitative oximetry.

Journal of Magnetic Resonance
Sankaran SubramanianMurali C Krishna

Abstract

A novel time-domain spectroscopic EPR imaging approach, that is a unique combination of already known techniques, is described. The first one is multi-gradient Single Point Imaging involving pure phase-encoding where the oximetry is based on T(2)(∗). Line width derived from T(2)(∗) is subject to susceptibility effects and therefore needs system-dependent line width calibrations. The second approach utilizes the conventional 90°-τ-180° Spin-Echo pulse sequence where the images are obtained by the filtered back-projection after FT of the echoes collected under frequency-encoding gradients. The spatially resolved oximetry information is derived from a set of T(2)-weighted images. The back-projection images suffer susceptibility artifacts with resolution determined by T(2)(∗), but the oximetry based on T(2) is quite reliable. The current approach combines Single Point Imaging and the Spin-Echo procedure to take advantage the enhanced spatial resolution associated with the former and the T(2) dependent contrast of the latter. Pairs of images are derived choosing two time points located at identical time intervals on either side of the 180° pulse. The refocusing pulse being exactly in the middle of the two points ensures that artifac...Continue Reading

References

Jul 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C T MoonenG Sobering
Jan 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·H FujiiL J Berliner
Jul 1, 1993·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G McGibneyA Crawley
Aug 1, 1997·Journal of Magnetic Resonance·P P BorbatJ H Freed
Oct 27, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R MurugesanM C Krishna
Jul 9, 1998·Journal of Magnetic Resonance·J H Ardenkjaer-LarsenK Golman
Apr 30, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Sankaran SubramanianMurali C Krishna
Sep 5, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Sankaran SubramanianMurali C Krishna
Mar 26, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Martyna ElasHoward J Halpern
Oct 22, 2003·Journal of Magnetic Resonance·Aharon BlankJack H Freed
Mar 10, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Colin MailerHoward J Halpern
Apr 6, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ken-ichiro MatsumotoMurali C Krishna
Mar 29, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Nallathamby DevasahayamMurali C Krishna
Apr 24, 2008·The Journal of Clinical Investigation·Shingo MatsumotoMurali C Krishna
Jul 3, 2008·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Samuel J LaRoqueXiaochuan Pan
Dec 23, 2011·Journal of Magnetic Resonance·Sankaran SubramanianMurali C Krishna

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Citations

Jun 24, 2015·Journal of Magnetic Resonance·Martin Spitzbarth, Malte Drescher
Oct 16, 2013·Journal of Magnetic Resonance·F GolubR Ahmad
Mar 28, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ken-Ichiro MatsumotoSankaran Subramanian
Aug 2, 2016·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Ken-Ichiro Matsumoto
Nov 17, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ken-Ichiro MatsumotoMurali C Krishna
Feb 2, 2021·Applied Magnetic Resonance·Joshua R Biller, Joseph E McPeak
Aug 26, 2021·Antioxidants & Redox Signaling·Jeffrey BrenderShun Kishimoto

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