Echo Particle Image Velocimetry for Estimation of Carotid Artery Wall Shear Stress: Repeatability, Reproducibility and Comparison with Phase-Contrast Magnetic Resonance Imaging

Ultrasound in Medicine & Biology
Arati GurungRobin Shandas

Abstract

Measurement of hemodynamic wall shear stress (WSS) is important in investigating the role of WSS in the initiation and progression of atherosclerosis. Echo particle image velocimetry (echo PIV) is a novel ultrasound-based technique for measuring WSS in vivo that has previously been validated in vitro using the standard optical PIV technique. We evaluated the repeatability and reproducibility of echo PIV for measuring WSS in the human common carotid artery. We measured WSS in 28 healthy participants (18 males and 10 females, mean age: 56 ± 12 y). Echo PIV was highly repeatable, with an intra-observer variability of 1.0 ± 0.1 dyn/cm2 for peak systolic (maximum), 0.9 dyn/cm2 for mean and 0.5 dyn/cm2 for end-diastolic (minimum) WSS measurements. Likewise, echo PIV was reproducible, with a low inter-observer variability (max: 2.0 ± 0.2 dyn/cm2, mean: 1.3 ± 0.1 dyn/cm2, end-diastolic: 0.7 dyn/cm2) and more variable inter-scan (test-retest) variability (max: 7.1 ± 2.3 dyn/cm2, mean: 2.9 ± 0.4 dyn/cm2, min: 1.5 ± 0.1 dyn/cm2). We compared echo PIV with the reference method, phase-contrast magnetic resonance imaging (PC-MRI); echo PIV-based WSS measurements agreed qualitatively with PC-MRI measurements (r = 0.89, p < 0.05). Significant ...Continue Reading

References

May 1, 1985·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·D N KuS Glagov
Nov 1, 1995·Journal of Magnetic Resonance Imaging : JMRI·J N OshinskiR I Pettigrew
Dec 11, 1999·JAMA : the Journal of the American Medical Association·A M MalekS Izumo
Apr 23, 2003·Ultrasound in Medicine & Biology·Piero TortoliDaniele Righi
Feb 14, 2004·Ultrasound in Medicine & Biology·Andrew WalkerPer Ask
Oct 29, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A F StalderM Markl
Nov 29, 2008·Arteriosclerosis, Thrombosis, and Vascular Biology·C G Caro
Jun 1, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Andreas HarloffMichael Markl
Feb 15, 2011·Ultrasound in Medicine & Biology·Fuxing ZhangRobin Shandas
Feb 13, 2013·Atherosclerosis·Jonathan P MynardDavid A Steinman
Jun 19, 2013·Magnetic Resonance Imaging·Michael MarklAndreas Harloff
Jun 25, 2013·Ultrasound in Medicine & Biology·Bin ZhouMeng-Xing Tang
Jan 18, 2014·Journal of Magnetic Resonance Imaging : JMRI·Wouter V PottersAart J Nederveen

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Citations

Dec 28, 2017·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Misun HwangThierry A G M Huisman
May 11, 2021·Surgical Technology International·Stefan EngelhardMichel M P J Reijnen

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