Echocardiographic indices and severity of mitral regurgitation in dogs with preclinical degenerative mitral valve disease

Journal of Veterinary Internal Medicine
Éva Larouche-LebelMark A Oyama

Abstract

Describing severity of mitral regurgitation (MR) in dogs with degenerative mitral valve disease (DMVD) is challenging. Mitral regurgitant fraction (RF), effective regurgitant orifice area (EROA), and the ratio of mitral regurgitant to aortic flow (QMR :QAo ) can be calculated from routine echocardiographic measurements and provide additional information regarding MR severity. Fifty-seven dogs with preclinical DMVD including 36 without and 21 with cardiomegaly. Prospective observational study. The expected relationships among RF, EROA, and QMR :QAo and 1-dimensional measurements including left atrium to aortic root diameter ratio (LA:Ao) and normalized left ventricular internal dimension at end-diastole (LVIDdN) were mathematically derived and calculated using echocardiographic data from the study population. Nonlinear goodness of fit was determined by calculation of the root mean standard error. The correlations between 1-dimensional and multidimensional indices were analyzed using receiver operating characteristic curves. The relationships among RF, EROA, QMR :QAo , and both LA:Ao and LVIDdN were curvilinear, and the multidimensional indices differentiated MR of variable severity. By contrast, 1-dimensional measurements were i...Continue Reading

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Citations

Jan 17, 2020·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Brian A Scansen, Randi Drees
Jan 17, 2020·Journal of Veterinary Internal Medicine·Brian A Scansen, Randi Drees
Dec 2, 2020·BMC Veterinary Research·Pinar LeventZeki Yilmaz
Dec 5, 2020·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·C BourguignonR Pariaut
May 6, 2021·Journal of Veterinary Internal Medicine·Tommaso VezzosiOriol Domenech

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