Echocardiographic measurement of epicardial adipose tissue thickness in patients with microvascular angina

Interventional Medicine & Applied Science
Macit KalçıkYusuf Karavelioğlu

Abstract

Impaired coronary microcirculation, inflammation, and endothelial dysfunction were reported etiological factors for microvascular angina (MVA). Recently, increased epicardial adipose tissue (EAT) thickness has been associated with hypertension, metabolic syndrome, and coronary artery disease in general population. In this study, we aimed to evaluate the EAT thickness in patients with MVA. This study enrolled 200 patients (83 males; mean age: 55.4 ± 8.2 years) who have been diagnosed with MVA and 200 controls (89 males; mean age: 54.4 ± 8.5 years). All patients underwent transthoracic echocardiography, and EAT thickness was measured from a parasternal long-axis view as the hypoechoic space on the right ventricular free wall. The mean EAT thickness was significantly higher in MVA patients than the controls (5.5 ± 1.1 vs. 4.9 ± 0.7 mm; p < 0.001). Multiple logistic regression analysis showed that increased EAT thickness was an independent predictor of MVA (OR = 1.183, 95% CI = 1.063-1.489; p = 0.023). In receiver operating characteristic curve analyses, EAT thickness above 5.3 mm predicted MVA with a sentivity of 68% and a specificity of 63% (AUC = 0.711, 95% CI = 0.659-0.762; p < 0.001). The EAT thickness was observed significant...Continue Reading

References

Jan 1, 1989·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J M MarchingtonC M Pond
Nov 14, 2000·Arteriosclerosis, Thrombosis, and Vascular Biology·K MiyataA Takeshita
Apr 5, 2003·The International Journal of Biochemistry & Cell Biology·Stefan EngeliArya M Sharma
Oct 29, 2003·Circulation·Tomasz MazurekYi Shi
Sep 28, 2005·Nature Clinical Practice. Cardiovascular Medicine·Gianluca IacobellisArya M Sharma
Jul 11, 2006·The American Journal of Medicine·Todd HurstChristopher P Appleton
Apr 21, 2007·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·S W Rabkin
May 12, 2007·The American Journal of Cardiology·Gianluca IacobellisGiuseppe Barbaro
Jun 2, 2007·American Heart Journal·Harold S Sacks, John N Fain
Dec 25, 2007·Progress in Cardiovascular Diseases·Narbeh MelikianPhilip A MacCarthy
Apr 9, 2009·JAMA : the Journal of the American Medical Association·Anita PhanC Noel Bairey Merz
Aug 29, 2009·Journal of the American College of Cardiology·Richard O Cannon
Dec 1, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Gianluca Iacobellis, Howard J Willens
Feb 9, 2010·International Journal of Cardiology·Mukesh SinghSandeep Khosla
May 6, 2011·Diabetes Care·Patricia Iozzo
Dec 3, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Cheng ChenC Noel Bairey Merz

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Clinical Investigation
Hiroshi Suzuki
Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır
Serpil EroğluHaldun Müderrisoğlu
Recenti progressi in medicina
Priscilla LamendolaGaetano A Lanza
© 2021 Meta ULC. All rights reserved