Echocardiographic parameters and renal outcomes in patients with preserved renal function, and mild- moderate CKD

BMC Nephrology
Thomas A MavrakanasDavid M Charytan

Abstract

Echocardiographic characteristics across the spectrum of chronic kidney disease (CKD) have not been well described. We assessed the echocardiographic characteristics of patients with preserved renal function and mild or moderate CKD referred for echocardiography and determined whether echocardiographic parameters of left ventricular (LV) and right ventricular (RV) structure and function were associated with changes in renal function and mortality. This retrospective cohort study enrolled all adult patients who had at least one trans-thoracic echocardiography between 2004 and 2014 in our institution. The composite outcome of doubling of serum creatinine or initiation of maintenance dialysis or kidney transplantation was the primary outcome. Mortality was the secondary outcome. 29,219 patients were included. Patients with worse renal function had higher prevalence of structural and functional LV and RV abnormalities. Higher estimated glomerular filtration rate (eGFR) was independently associated with preserved LV ejection fraction, preserved RV systolic function, and lower LV mass, left atrial diameter, pulmonary artery pressure, and right atrial pressure, as well as normal RV structure. 1041 composite renal events were observed....Continue Reading

References

Feb 8, 2006·Circulation·Hans L HillegeDirk J van Veldhuisen
Mar 29, 2008·Journal of the American College of Cardiology·Anju NohriaJames A Hill
Nov 19, 2008·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Mayu NishioKazuhiro Yamamoto
Feb 14, 2009·Journal of the American College of Cardiology·Wilfried MullensW H Wilson Tang
May 10, 2011·Heart Failure Reviews·Branko BraamCarlo Gaillard
Sep 9, 2011·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Michael PavlicekChristian Seiler
May 15, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Meyeon ParkCarmen A Peralta
Sep 1, 2012·Journal of the American Society of Nephrology : JASN·Meyeon ParkUNKNOWN Chronic Renal Insufficiency Cohort (CRIC) Study Group
Feb 22, 2013·The American Journal of the Medical Sciences·Jer-Ming ChangHung-Chun Chen
Aug 16, 2016·Clinical Journal of the American Society of Nephrology : CJASN·Kathrin UnterstellerGunnar H Heine
Feb 2, 2017·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Leila R ZelnickNisha Bansal

❮ Previous
Next ❯

Citations

Feb 1, 2021·European Heart Journal Cardiovascular Imaging·Junichi IshigamiKunihiro Matsushita
Nov 26, 2021·Echocardiography·Ana TanasaAdrian Covic
Jan 1, 2022·The International Journal of Cardiovascular Imaging·Jacob ChristensenTor Biering-Sørensen

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.