Echocardiographic parameters associated with biventricular circulation and right ventricular growth following right ventricular decompression in patients with pulmonary atresia and intact ventricular septum: Results from a multicenter study

Congenital Heart Disease
Shiraz A MaskatiaRitu Sachdeva

Abstract

In patients with pulmonary atresia, intact ventricular septum (PA/IVS) following right ventricular (RV) decompression, RV size and morphology drive clinical outcome. Our objectives were to (1) identify baseline and postdecompression echocardiographic parameters associated with 2V circulation, (2) identify echocardiographic parameters associated with RV growth and (3) describe changes in measures of RV size and changes in RV loading conditions. We performed a retrospective analysis of patients who underwent RV decompression for PA/IVS at four centers. We analyzed echocardiograms at baseline, postdecompression, and at follow up (closest to 1-year or prior to Glenn circulation). Eighty-one patients were included. At last follow-up, 70 (86%) patients had 2V circulations, 7 (9%) had 1.5 ventricle circulations, and 4 (5%) had single ventricle circulations. Follow-up echocardiograms were available in 43 (53%) patients. The majority of patients had improved RV systolic function, less tricuspid regurgitation (TR), and more left-to-right atrial shunting at a median of 350 days after decompression. Multivariable analysis demonstrated that larger baseline tricuspid valve (TV) z-score (P = .017), ≥ moderate baseline TR (P = .045) and smalle...Continue Reading

References

Oct 22, 1987·The New England Journal of Medicine·R D Mosteller
Sep 23, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Satoshi NumataHideo Ohuchi
Mar 31, 2004·The Journal of Thoracic and Cardiovascular Surgery·David A AshburnUNKNOWN Congenital Heart Surgeons Study members
Oct 11, 2005·The Journal of Thoracic and Cardiovascular Surgery·Piers E F DaubeneyUNKNOWN UK and Ireland Collaborative Study of Pulmonary Atresia with Intact Ventricular Septum
Apr 15, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Michael D PettersenRichard A Humes
Jun 24, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R IacobelliS P Sanders
Dec 5, 2009·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Abdenasser DrighilFadl AlFadly
Sep 9, 2010·The Thoracic and Cardiovascular Surgeon·J CleuziouR Lange
Apr 14, 2012·Journal of the American College of Cardiology·Henry ChubbShakeel A Qureshi
Oct 19, 2012·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Babar Sultan HasanFrank A Pigula
Aug 26, 2014·The Annals of Thoracic Surgery·Adriaan W SchneiderMark G Hazekamp
Oct 10, 2015·Journal of the American College of Cardiology·Kavitha N PundiFrank Cetta
Oct 23, 2015·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Fei-Fei LiShu Chen
Apr 28, 2016·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Yasuhiro KotaniShunji Sano
Aug 5, 2016·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·David M KwiatkowskiCatherine D Krawczeski
Mar 21, 2017·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·William A ZoghbiNeil J Weissman

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