PMID: 3768779Jul 1, 1986Paper

Echocardiographic studies during stress testing using cold pressor test combined with hand grip exercise in asymptomatic patients with severe aortic regurgitation

The Canadian Journal of Cardiology
A YousofN Hayat

Abstract

The aim of this study was to evaluate stress combining a cold pressor test and hand grip exercise during echocardiographic investigation of predominantly young asymptomatic patients with severe aortic regurgitation. Thirty five patients were catheterised and divided into two groups. Group A (16 cases) with abnormal ejection fraction by angiocardiography (less than 50%) and Group B (19 cases) with normal ejection fraction (greater than or equal to 50%). The above stress test altered significantly the blood pressure and heart rate in both groups. However, echocardiographic end systolic diameter, end diastolic diameter and fractional shortening were significantly worse during stress test only in Group A but not in Group B. In addition when an end systolic diameter greater than or equal to 48 mm is used as a predictor of abnormal ejection fraction, its sensitivity (100%) and specificity (83%) during stress is only marginally superior to the results obtained at rest. Similarly fractional shortening decrease of 10% or more during stress was no better than resting end systolic diameter parameter. The modified peak systolic pressure-end systolic volume slope demonstrated diminished systolic function in Group A in comparison to Group B....Continue Reading

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