Echolucent plaques are associated with high risk of ischemic cerebrovascular events in carotid stenosis: the tromsø study

Circulation
E B MathiesenO Joakimsen

Abstract

The purpose of the study was to assess in a prospective design whether plaque morphology is associated with risk of ischemic stroke and other cerebrovascular events in subjects with carotid stenosis. A total of 223 subjects with carotid stenosis (123 with 35% to 49% degree of stenosis, 100 with 50% to 99% stenosis) and 215 control subjects matched by age and sex who participated in a population health survey at baseline were followed up for 3 years. Plaque echogenicity was assessed by ultrasound at baseline and scored as echolucent, predominantly echolucent, predominantly echogenic, or echogenic. Forty-four subjects experienced >/=1 ischemic cerebrovascular events in the follow-up period. Plaque echogenicity, degree of stenosis, and white blood cell count were independent predictors of cerebrovascular events. The unadjusted relative risk for cerebrovascular events was 13.0 (95% CI 4.5 to 37.4) in subjects with echolucent plaques and 3.7 (95% CI 0.7 to 18.2) in subjects with echogenic plaques when subjects without stenosis were used as the reference. The adjusted relative risk for cerebrovascular events in subjects with echolucent plaques was 4.6 (95% CI 1.1 to 18.9), and there was a significant linear trend (P=0.015) for higher...Continue Reading

References

Jan 23, 1992·The New England Journal of Medicine·V FusterJ H Chesebro
Apr 1, 1990·European Journal of Vascular Surgery·E J LeenG D Shanik
Jul 1, 1989·The Australian and New Zealand Journal of Surgery·C M SteffenR J Lusby
Dec 1, 1987·American Journal of Surgery·L W O'HolleranJ M Johnson
Nov 1, 1983·Ultrasound in Medicine & Biology·M K WolversonG J Peterson
Jul 1, 1995·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·E M CaveJ P Woodcock
May 1, 1995·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·N el-BarghoutyV Bahal
Jan 1, 1995·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·R J HoldsworthD K Harrison
May 1, 1997·The New England Journal of Medicine·A P BurkeR Virmani
Feb 19, 1998·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M L GrønholdtH Sillesen
Jul 4, 2001·Cerebrovascular Diseases·E B MathiesenK H Bønaa

❮ Previous
Next ❯

Citations

Apr 14, 2007·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·W Lang
Apr 21, 2010·Neuroradiology·Michael Rosenkranz, Christian Gerloff
Nov 13, 2007·Journal of Neurology·L EspositoH Poppert
Jun 9, 2009·Current Atherosclerosis Reports·Henrik Sillesen
Jan 28, 2012·Current Atherosclerosis Reports·Smita I Negi, Vijay Nambi
Feb 4, 2011·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Gagandeep S Gurm, Ahmed Tawakol
Jun 24, 2004·Neurobiology of Aging·Allison B ReissMony J de Leon
Dec 7, 2002·Ultrasound in Medicine & Biology·Yoji NagaiE Jeffrey Metter
Jul 25, 2003·Ultrasound in Medicine & Biology·Jon BangHans Olav Myhre
Jul 25, 2003·Ultrasound in Medicine & Biology·Isabelle MayorRoman Sztajzel
Dec 19, 2002·Neuroimaging Clinics of North America·Marie-Louise Moes Grønholdt
Feb 19, 2002·Journal of the American College of Surgeons·G Patrick Clagett
Dec 6, 2012·Nature Communications·Fredrik H KarlssonJens Nielsen
Feb 28, 2008·Nature Clinical Practice. Cardiovascular Medicine·Andreas KönigVolker Klauss
Aug 9, 2011·European Heart Journal·Quirijn J A van den BouwhuijsenJacqueline C M Witteman
Mar 23, 2011·International Journal of Epidemiology·Bjarne K JacobsenInger Njølstad
Jul 18, 2006·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Shane K KimRobert A Stoltz
Sep 2, 2010·Topics in Magnetic Resonance Imaging : TMRI·Niranjan BaluChun Yuan
Mar 28, 2006·Cardiovascular Ultrasound·Christina PetersenEugenio Picano
Jan 31, 2006·Cardiovascular Ultrasound·Stavros K KakkosGeorge Geroulakos
Mar 23, 2010·Cardiovascular Ultrasound·Maria Elena GianicoloMaurizio Portaluri
Sep 20, 2011·Cardiovascular Ultrasound·Liz Andréa V BaronciniDalton B Précoma
Feb 28, 2007·Thrombosis Journal·Liz Andréa Villela BaronciniLuiz Otavio Murta
Oct 21, 2006·Neurosurgery·Ricardo A HanelL Nelson Hopkins
Apr 13, 2011·International Heart Journal·Marco Matteo CicconeStefano Favale
Oct 18, 2006·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Giorgio M BiasiMarialuisa Lavitrano
Apr 16, 2013·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·B Patrice Mwipatayi, Alarick Picardo
Feb 24, 2007·Vascular Health and Risk Management·Roman Komorovsky, Alessandro Desideri
Dec 24, 2004·AJR. American Journal of Roentgenology·Kiran R NandalurChristopher M Kramer
Aug 2, 2013·Journal of Atherosclerosis and Thrombosis·Tamio TeramotoKoutaro Yokote

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Related Papers

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
N M El-BarghoutyV Bahal
European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
N M El-BarghoutyA N Nicolaides
European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
© 2021 Meta ULC. All rights reserved