ECMO for cardiac rescue in a neonate with accidental amiodarone overdose.

Clinical Research in Cardiology : Official Journal of the German Cardiac Society
Nikolaus A HaasDeniz Kececioglu

Abstract

Intravenous (IV) amiodarone hydrochloride has proven to be a very effective antiarrhythmic treatment option for a variety of ventricular and supraventricular arrhythmias in adults and paediatric patients. Amiodarone is known to have significant side effects and these especially include profound hypotension in animals and adults, vasodilatation, negative inotropic effects, and significant bradycardia especially when administered intravenously. Special caution is warranted in patients with decreased contractility and end-stage heart failure. We present a case of accidental amiodarone overdose in a newborn treated for atrial flutter resulting in cardiovascular collapse. The patient could be rescued by rapid initiation of VA-ECMO treatment. The patient survived without neurological damage.

References

Sep 1, 1984·Journal of the American College of Cardiology·E J KosinskiO S LeLand
Jan 1, 1994·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·W BannerD D Vernon
Jul 1, 1993·American Heart Journal·N TwidaleR J McRitchie
Apr 1, 1996·Journal of the American College of Cardiology·J C PerryJ J Lamberti
Nov 14, 1997·The American Journal of Cardiology·H M HoffmeisterL Seipel
Mar 15, 2000·Journal of the American College of Cardiology·L A LisowskiE J Meijboom
May 25, 2001·Critical Care Medicine·G M Auzinger, C D Scheinkestel
Mar 27, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Gregor M WalkerCarl Davis
Jul 2, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Andrew DurwardSam D Shemie
Sep 26, 2003·European Journal of Pediatrics·Silvia BurriUrs Bauersfeld
Dec 17, 2003·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Geraldine Y T NgLinda J Murdoch
May 26, 2004·Zeitschrift für Kardiologie·N A HaasP Pohlner
Apr 7, 2005·Fundamental & Clinical Pharmacology·Marcos Adriano Lessa, Eduardo Tibiriçá
Dec 1, 2005·Circulation·J Philip SaulUNKNOWN Intravenous Amiodarone Pediatric Investigators
Jun 27, 2006·The Annals of Thoracic Surgery·Vinod H ThouraniJoseph M Forbess
Jan 18, 2007·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Jörg S SachwehSabine H Däbritz
Sep 12, 2007·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Walter KnirschUrs Bauersfeld

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Citations

Mar 31, 2011·Pediatric Cardiology·Jack Christian SalernoDavid Michael McMullan
Sep 12, 2012·Case Reports in Pediatrics·Michael FroehleEugen Sandica
Aug 22, 2014·Herzschrittmachertherapie & Elektrophysiologie·Jan-Hendrik NürnbergJürgen Siebels
Jul 14, 2010·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Martin SchwaiblmairWolfgang von Scheidt
May 24, 2013·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·D W de LangeJ Meulenbelt
Oct 8, 2013·Pediatric Clinics of North America·Fermin BarruetoMaryann Mazer-Amirshahi
Mar 8, 2014·Heart and Vessels·Filippo BenassiMarco Meli
Mar 22, 2019·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Justin LewisT Albertson
Aug 17, 2021·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Cameron UpchurchRobert G Hendrickson

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