PMID: 8594595Jan 1, 1996Paper

EcoCyc: an encyclopedia of Escherichia coli genes and metabolism

Nucleic Acids Research
P D KarpA Pelligrini-Toole

Abstract

The encyclopedia of Escherichia coli genes and metabolism (EcoCyc) is a database that combines information about the genome and the intermediary metabolism of E.coli. It describes 2034 genes, 306 enzymes encoded by these genes, 580 metabolic reactions that occur in E.coli and the organization of these reactions into 100 metabolic pathways. The EcoCyc graphical user interface allows query and exploration of the EcoCyc database using visualization tools such as genomic map browsers and automatic layouts of metabolic pathways. EcoCyc spans the space from sequence to function to allow investigation of an unusually broad range of questions. EcoCyc can be thought of as both an electronic review article, because of its copious references to the primary literature, and as an in silico model of E.coli that can be probed and analyzed through computational means.

References

Aug 1, 1992·Computer Applications in the Biosciences : CABIOS·P D Karp
Sep 1, 1994·Nucleic Acids Research·A Bairoch

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Citations

Jul 22, 1998·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·D ThieffryJ Collado-Vides
Aug 1, 1997·Electrophoresis·R A VanBogelenF C Neidhardt
Apr 1, 1996·Trends in Genetics : TIG·K E Rudd
Jun 12, 1996·Gene·S M Paley, P D Karp
Jul 31, 2003·Pharmacology & Therapeutics·Pamela M CarrollKevin FitzGerald
Aug 26, 1998·Bio Systems·H OgataM Kanehisa
Apr 1, 1997·Current Opinion in Biotechnology·D C Cameron, F W Chaplen
Jan 1, 1997·Nature Biotechnology·B O Palsson
Dec 3, 1999·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·C V Forst, K Schulten
Jan 1, 1996·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·P D Karp, S Paley
Jan 14, 2005·Bioinformatics·Ross D KingGeorge M Coghill
Apr 9, 2011·Database : the Journal of Biological Databases and Curation·Augusto F VellozoStefano Colella
Jan 1, 1997·Nucleic Acids Research·P D KarpM Krummenacker
Feb 21, 1998·Nucleic Acids Research·A M HuertaJ Collado-Vides
Dec 2, 2009·Nucleic Acids Research·Alex FrolkisDavid S Wishart
Nov 22, 2011·Nucleic Acids Research·Anne MorgatAlain Viari
Nov 3, 2001·Genome Research·R Friedman, A L Hughes
Sep 16, 2011·Science Signaling·Avi Ma'ayan
Nov 15, 2006·BMC Bioinformatics·Ethan G CeramiChris Sander
Feb 14, 2008·BMC Bioinformatics·K E Whelan, R D King
Sep 25, 2007·BMC Evolutionary Biology·Merav ParterUri Alon
Mar 21, 2007·Genome Biology·Imre VastrikLincoln Stein
Jan 10, 2013·PLoS Computational Biology·David S Wishart
Nov 15, 2000·Biological Chemistry·J van HeldenS J Wodak
Sep 24, 1999·Journal of the American Medical Informatics Association : JAMIA·R O Chen, R B Altman
Nov 27, 2014·Metabolites·Paolo CazzanigaMarco Vanoni
Jul 22, 1996·FEBS Letters·C Ouzounis, N Kyrpides
Jul 7, 2009·Trends in Microbiology·James C HuDeborah A Siegele
Mar 14, 2009·Journal of Molecular Biology·Karoline FaustJacques van Helden
Jan 9, 2007·Current Opinion in Chemical Biology·Paul D ThomasSuzanna Lewis
Jun 7, 2014·Biotechnology and Bioengineering·Michael WeinerDirk Weuster-Botz
Nov 14, 2007·Structure·Emmanuel D Levy
Apr 19, 2015·BMC Bioinformatics·Alison CallahanMichel Dumontier
Apr 27, 2010·Molecular BioSystems·Gregory Vey, Gabriel Moreno-Hagelsieb

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