Economic analysis of VenUS I, a randomized trial of two bandages for treating venous leg ulcers

The British Journal of Surgery
C P IglesiasVenUS I collaborators

Abstract

The study investigated the cost-effectiveness of four-layer and short-stretch compression bandages for treating venous leg ulcers. Cost-effectiveness and cost-utility analyses were performed using patient-level data collected alongside the VenUS I leg ulcer study. The perspective for the economic analysis was that of the UK National Health Service (NHS) and Personal Social Service. The time horizon for the analysis was 1 year after recruitment. Health benefit was measured as differences in ulcer-free days and quality-adjusted life years (QALYs). The mean healing time for ulcers treated with four-layer bandages was 10.9 (95 per cent confidence interval (c.i.) -6.8 to 29.1) days less than that for ulcers treated with short-stretch bandages. Mean average difference in QALYs between compression systems was -0.02 (95 per cent c.i. -0.08 to 0.04). The four-layer bandage cost a mean of pound 227.32 (95 per cent c.i. pound 16.53 to pound 448 .30) less per patient per year than the short-stretch bandage. On average, four-layer bandaging was associated with greater health benefits and lower costs than short-stretch bandaging.

References

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Sep 24, 2004·The British Journal of Surgery·E A NelsonUNKNOWN VenUS I collaborators

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Citations

Aug 27, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Cynthia P IglesiasNicky A Cullum
Oct 4, 2012·BMC Health Services Research·Ba' PhamUNKNOWN Canadian Bandaging Trial Group
Jun 16, 2011·Clinical, Cosmetic and Investigational Dermatology·Paul Bevis, Jonothan Earnshaw
Dec 5, 2015·International Wound Journal·Rosana E NormanNicholas Graves
Jun 19, 2016·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Seshadri RajuThomas F O'Donnell
Jun 23, 2015·The British Journal of Dermatology·H Partsch, P Mortimer
Jun 4, 2015·Phlebology·Lavanya VaratharajanAlun Huw Davies
Feb 15, 2012·Phlebology·P M Bevis, J J Earnshaw
Sep 10, 2014·The Cochrane Database of Systematic Reviews·E Andrea Nelson, Sally E M Bell-Syer
Dec 18, 2013·Advances in Skin & Wound Care·Siobhan O'Connor, Siobhan Murphy
Nov 16, 2012·The Cochrane Database of Systematic Reviews·Susan O'MearaJo C Dumville
Apr 22, 2011·The British Journal of Surgery·L-H ChuangUNKNOWN VenUS III team
Mar 19, 2021·The Cochrane Database of Systematic Reviews·Niamh Em McLainPinar Avsar
Sep 24, 2004·The British Journal of Surgery·E A NelsonUNKNOWN VenUS I collaborators
Jul 27, 2021·The Cochrane Database of Systematic Reviews·Chunhu ShiGill Norman

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