PMID: 2117144Jan 1, 1990Paper

Economic and long-term benefits of ribavirin therapy on respiratory syncytial virus infection

Lung
N J Snell

Abstract

Ribavirin is a broad-spectrum antiviral agent. Administered as an aerosol, it has been shown to be clinically effective in improving the signs and symptoms of viral bronchiolitis in infancy, particularly cases due to respiratory syncytial virus (RSV). This paper reviews the evidence for economic and/or long-term clinical benefits from using ribavirin in the acute illness. There are data to suggest that use of ribavirin may lead to a reduction in therapeutic interventions and duration of hospital stay, with associated savings in hospital costs. Ribavirin reduces the production of RSV-specific IgE, and (in vitro) inhibits the release of inflammatory mediators from mast cells, suggesting that there could be beneficial effects on the incidence of postbronchiolitis wheezing. Confirmatory studies are in progress.

References

Dec 1, 1990·Critical Care Medicine·K MeertA Sarnaik
Jan 1, 1989·Thorax·A D Milner, M Murray
Jan 1, 1989·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·W W Busse
Jun 1, 1989·American Journal of Epidemiology·A L WrightC J Holberg
Nov 9, 1985·Lancet·R M BuchdahlJ D Warner
Aug 1, 1986·Antimicrobial Agents and Chemotherapy·B E Gilbert, V Knight
Feb 1, 1988·The Journal of Pediatrics·B VolovitzP L Ogra
May 1, 1988·Digestive Diseases and Sciences·L BertarioF Berrino
Jun 1, 1986·Archives of Disease in Childhood·W BarryA Vardag
Feb 1, 1987·The Pediatric Infectious Disease Journal·W J RodriguezR H Parrott
Feb 1, 1987·Italian Journal of Neurological Sciences·M AlterL LaRue
Aug 1, 1987·Pediatric Annals·D A Laufer, P J Edelson
Sep 1, 1986·Pediatric Infectious Disease·B J Sullivan
Dec 6, 1985·JAMA : the Journal of the American Medical Association·C B HallK C Schnabel
Jan 2, 1986·The New England Journal of Medicine·J B McCormickR Belmont-Williams
Nov 1, 1985·Archives of Disease in Childhood·M S WebbA S Swarbrick
Mar 1, 1984·American Journal of Diseases of Children·K McIntoshB Goodspeed
May 20, 1983·JAMA : the Journal of the American Medical Association·C B HallW J Hall
Aug 12, 1982·The New England Journal of Medicine·N E MacDonaldJ A Manning
Jan 1, 1959·Archiv für die gesamte Virusforschung·R B HEATH, D A TYRRELL

❮ Previous
Next ❯

Citations

May 1, 1993·Journal of Gastroenterology and Hepatology·M Gracey
Nov 4, 2000·Expert Opinion on Investigational Drugs·S Shigeta
Nov 1, 1992·Clinical Pediatrics·M I Marks
Aug 1, 1996·Journal of the American Academy of Nurse Practitioners
Jan 1, 1993·Postgraduate Medicine·R J Kuzel, D J Clutter
Aug 16, 2001·Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy·Philip R. Wyde

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.