PMID: 2116582Aug 6, 1990Paper

Economic assessments in randomized controlled trials

The Medical Journal of Australia
C J Bulpitt, A E Fletcher

Abstract

When comparing costs and benefits of different medical strategies, cost-effectiveness analysis, cost-utility analysis and cost-benefit analysis may be used. Both direct and indirect costs and benefits must be considered. Integrating survival with a measure of quality of life such as a health status index permits calculation of quality of life adjusted years of survival (QALYS). In any trial where it is expected that a more expensive treatment is the most effective, a full economic assessment should be made. Examples are provided from the use of verapamil and propranolol in hypertension, naftidrofuryl in stroke and auranofin in the treatment of rheumatoid arthritis.

References

Dec 12, 1987·British Medical Journal·A Maynard
Sep 1, 1974·British Medical Bulletin·A Williams
Jun 1, 1984·Controlled Clinical Trials·M F Drummond, G L Stoddart
Apr 1, 1980·Archives of General Psychiatry·B A WeisbrodL I Stein

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Citations

Sep 1, 1995·Neurosurgery·M J Rutigliano
Mar 24, 1998·International Journal of Technology Assessment in Health Care·D CoyleM F Drummond

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