Economic burden of lung cancer: A retrospective cohort study in South Korea, 2002-2015

PloS One
Soo Min JeonHae-Young Park

Abstract

We evaluated the survival rates and medical expenditure in patients with lung cancer using a nationwide claims database in South Korea. A retrospective observational cohort study design was used, and 2,919 lung cancer patients and their matched controls were included. Medical expenditures were analyzed with the Kaplan-Meier sample average method, and patients were categorized into 4 groups by operation and primary treatment method (i.e. Patients with operation: OP = surgery, OP+CTx/RTx = surgery with anti-cancer drugs or radiotherapy; Patients without operation: CTx/RTx = anti-cancer drugs or radiotherapy, Supportive treatment). The 5-year medical expenditure per case was highest in the OP+CTx/RTx group ($36,013), followed by the CTx/RTx ($23,134), OP ($22,686), and supportive treatment group ($3,700). Lung cancer-related anti-cancer drug therapy was the major cost driver, with an average 53% share across all patients. Generalized linear regression revealed that monthly medical expenditure in lung cancer patients, after adjustment for follow-up month, was approximately 3.1-4.3 times higher than that in the control group (cost ratio for OP = 3.116, OP+CTx/RTx = 3.566, CTx/RTx = 4.340, supportive treatment = 4.157). The monthly m...Continue Reading

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Citations

Oct 25, 2020·Journal of Clinical Medicine·Ramon Andrade de Mello, Giovanna Araújo Amaral
Jun 27, 2021·Health Economics Review·Irfan CicinUNKNOWN Turkish Respiratory Society
Dec 3, 2021·Journal of Managed Care & Specialty Pharmacy·Xinke ZhangFrancois-Xavier Lamy

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