Economic burden of varicella complications in two referral centers in Mexico

Human Vaccines & Immunotherapeutics
Mercedes Macias-ParraRodolfo Norberto Jiménez-Juárez

Abstract

Varicella-zoster virus causes varicella (chicken-pox), mainly in young children. Most cases are mild but serious complications can occur, resulting in significant morbidity and mortality. The objective of this study was to estimate the cost burden of varicella hospitalizations in two pediatric reference hospitals in Mexico. This retrospective observational study collected data on patients aged <18 years admitted to two third-level referral hospitals in Mexico. Cases were identified from hospital records using International Classification of Diseases Ninth Revision (ICD-9) codes 052 Chickenpox, or Tenth Revision (ICD-10) codes B01 Varicella (chickenpox). Data on demographic and clinical characteristics and resource use were collected from hospital records. Costs for hospital stay and interventions were obtained from the Mexican Institute for Social Security for 2015 and updated to 2017 costs. A total of 172 hospitalized varicella clinically-confirmed cases and 121 varicella- contacts (with epidemiological linkage to a clinically-confirmed case) were included. Thirty eight of the 172 cases (22.0%) experienced complications. There were no deaths. The median duration of hospitalization was 12 days for cases and 23 days for contacts...Continue Reading

References

Sep 24, 2002·Revista Panamericana De Salud Pública = Pan American Journal of Public Health·Xavier Sáez-LlorensMaría Del Pilar Rubio
Nov 16, 2004·Vaccine·Jonathan R CarapetisNigel Curtis
Oct 19, 2006·Lancet·Ulrich Heininger, Jane F Seward
May 29, 2012·Revista de salud pública·Nelson Alvis-GuzmánFernando De la Hoz-Restrepo
Mar 13, 2016·Jornal de pediatria·Alessandra de Martino Mota, Filipe Anibal Carvalho-Costa
Jan 1, 2013·Value in Health Regional Issues·Ozden TurelRengin Siraneci

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