Economic evaluation of diagnosing and excluding ectopic pregnancy.

Human Reproduction
C J WedderburnA W Horne

Abstract

The diagnosis of ectopic pregnancy in women presenting in early pregnancy is often protracted, relying on costly investigations that are psychologically burdensome to the patient. The aim of this study was to evaluate the financial costs to the health services in Scotland of the current methods used to diagnose and exclude ectopic pregnancy, and compare these with that of a theoretical single diagnostic serum biomarker. We conducted a retrospective cost-description analysis (with and without costs of diagnostic laparoscopy) of the health-care costs incurred by all patients presenting to a large Scottish teaching hospital between June and September 2006 with pain and bleeding in early pregnancy, where ectopic pregnancy was not excluded. Additionally, a cost minimization analysis was performed for the costs of current ectopic pregnancy investigations versus those of a theoretical single diagnostic serum biomarker. This included sensitivity analyses where the biomarker was priced at increasing values and assumed to have less than 100% diagnostic sensitivity and specificity. About 175 patients were eligible to be included in the analysis. Forty-seven per cent of patients required more than three visits to diagnose or exclude ectopi...Continue Reading

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Citations

Mar 3, 2012·Expert Reviews in Molecular Medicine·Andrew W Horne, Hilary O D Critchley
Jul 24, 2010·Molecular Human Reproduction·W C DuncanA W Horne
Jul 6, 2011·The Journal of Family Planning and Reproductive Health Care·Vanitha N SivalingamAndrew W Horne
Apr 6, 2013·BMC Pregnancy and Childbirth·Nancy N HamuraHolger W Unger
Nov 5, 2010·The Journal of Clinical Endocrinology and Metabolism·Andrew W HorneHilary O D Critchley
Nov 13, 2012·Gynecological Surgery·Sharon P RodriguesFrank W Jansen
Jun 25, 2013·Archives of Gynecology and Obstetrics·Poonam RanaFiroz Anwar
Mar 14, 2013·Expert Opinion on Medical Diagnostics·Shannon ReidGeorge Condous
Sep 13, 2011·American Journal of Obstetrics and Gynecology·Laila NurmohamedYaron Finkelstein
Sep 19, 2014·Molecular Human Reproduction·Stephen TongAndrew W Horne
Feb 1, 2017·Journal of Biomedical Semantics·Ferdinand DhombresJean-Marie Jouannic
Feb 24, 2012·Biology of Reproduction·Ruijin ShaoHåkan Billig
Nov 1, 2012·The Journal of Family Planning and Reproductive Health Care·Holger W UngerAndrew W Horne
Jun 6, 2021·Journal of Gynecology Obstetrics and Human Reproduction·Şule Yıldırım KöpükGürkan Kıran
Sep 22, 2017·Journal of Gynecology Obstetrics and Human Reproduction·P MauriceJ-M Jouannic

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